Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | KDR | P35968 | 3/20 | 0.58 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.57 |
| ▸ | TUBB | P07437 | 1/20 | 0.57 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.57 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.57 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.57 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.57 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.57 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.57 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.57 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.57 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.57 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.57 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.57 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.57 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.57 |
| ▸ | DHODH | Q02127 | 5/20 | 0.55 |
| ▸ | MEN1 | O00255 | 5/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23388895 | 1.00 | LMNA (0.58) | LMNAPOLBKDRTUBB4ATUBB | |
| SCHEMBL29898324 | 0.86 | MAPT (0.68) | LMNAPOLBKDRTUBB4ATUBB | |
| SCHEMBL23423252 | 0.86 | MAPT (0.68) | LMNAPOLBKDRTUBB4ATUBB | |
| SCHEMBL5953848 | 0.86 | LMNA (0.78) | LMNAPOLBTUBB4ATUBBTUBA3C | |
| SCHEMBL23388857 | 0.85 | DHODH (0.74) | LMNAPOLBKDRTUBB4ATUBB | |
| SCHEMBL5217337 | 0.83 | MEN1 (0.75) | LMNAPOLBKDRDHODHMEN1 | |
| SCHEMBL25246835 | 0.82 | DHODH (0.62) | LMNAPOLBKDRTUBB4ATUBB | |
| SCHEMBL30476156 | 0.82 | DHODH (0.62) | LMNAPOLBKDRTUBB4ATUBB | |
| SCHEMBL23388818 | 0.82 | MEN1 (0.53) | LMNAPOLBKDRTUBB4ATUBB | |
| SCHEMBL29888247 | 0.82 | MEN1 (0.53) | LMNAPOLBKDRTUBB4ATUBB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115279368-B | Heteroaryl compounds | 维瓦斯治疗公司 | 2024-05-24 | — | — | CN | disclosed |
| CN-115279368-A | Heteroaryl compounds | 维瓦斯治疗公司 | 2022-11-01 | — | — | CN | disclosed |