Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESRRG | P62508 | 13/20 | 0.48 |
| ▸ | ESR1 | P03372 | 7/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.48 |
| ▸ | ESRRB | O95718 | 7/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | MGLL | Q99685 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | STAT1 | P42224 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24688918 | 0.83 | ALDH1A1 (0.54) | ESRRGESR1KCNH2ESRRBCYP19A1 | |
| SCHEMBL24688546 | 0.82 | ESRRG (0.67) | ESRRGESR1KCNH2ESRRBMAPT | |
| SCHEMBL24688554 | 0.78 | ESRRG (0.61) | ESRRGESR1KCNH2ESRRBMAPT | |
| SCHEMBL24688559 | 0.78 | ESRRG (0.64) | ESRRGESR1KCNH2ESRRBMAPT | |
| SCHEMBL24688913 | 0.74 | ESRRG (0.57) | ESRRGESR1KCNH2ESRRBMAPT | |
| SCHEMBL24688923 | 0.72 | ESRRG (0.65) | ESRRGESR1KCNH2ESRRBCYP19A1 | |
| SCHEMBL29968359 | 0.71 | ESRRG (0.57) | ESRRGESR1KCNH2ESRRBMAPT | |
| SCHEMBL24688801 | 0.70 | ESRRG (0.68) | ESRRGESR1KCNH2ESRRBMGLL | |
| SCHEMBL24688550 | 0.70 | ESRRG (0.52) | ESRRGESR1KCNH2ESRRBMAPT | |
| SCHEMBL24688561 | 0.69 | ESRRG (0.51) | ESRRGESR1KCNH2ESRRBNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022245124-A1 | NOVEL ETHENE COMPOUND AND PHARMACEUTICAL COMPOSITION INCLUDING SAME AS ACTIVE INGREDIENT FOR PREVENTION OR TREATMENT OF CANCER | 재단법인 대구경북첨단의료산업진흥재단 | 2022-11-24 | — | — | WO | disclosed |