Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | NSD2 | O96028 | 1/20 | 0.44 |
| ▸ | BACE1 | P56817 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.43 |
| ▸ | RELA | Q04206 | 1/20 | 0.43 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.43 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.43 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.43 |
| ▸ | APP | P05067 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23320550 | 0.83 | NPC1 (0.57) | MAPTALDH1A1MEN1KMT2ANPC1 | |
| SCHEMBL29968961 | 0.83 | MAPT (0.42) | MAPTALDH1A1KDM4ENSD2BACE1 | |
| SCHEMBL3226759 | 0.77 | NPC1 (0.55) | MAPTALDH1A1KDM4ENSD2MEN1 | |
| SCHEMBL15910787 | 0.77 | MAPT (0.57) | MAPTALDH1A1KDM4ENSD2MEN1 | |
| SCHEMBL1663523 | 0.76 | ESR2 (0.51) | MAPTALDH1A1KDM4ENSD2MEN1 | |
| SCHEMBL3853197 | 0.76 | ESR2 (0.47) | MAPTALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL9926876 | 0.73 | ALDH1A1 (0.50) | MAPTALDH1A1KDM4ENSD2MEN1 | |
| SCHEMBL2264916 | 0.73 | ESR2 (0.47) | MAPTKDM4EMEN1KMT2ANPC1 | |
| SCHEMBL30943227 | 0.72 | ADORA1 (0.48) | MAPTMEN1KMT2ANPC1RAB9A | |
| SCHEMBL23320443 | 0.72 | ADORA1 (0.48) | MAPTMEN1KMT2ANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111662232-B | Small molecule compound with 2H-indazole structure and synthesis and application thereof | 中国科学院上海药物研究所 | 2022-08-02 | — | — | CN | disclosed |