Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 1/20 | 0.78 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.78 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.78 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.78 |
| ▸ | HTT | P42858 | 4/20 | 0.71 |
| ▸ | TP53 | P04637 | 1/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.68 |
| ▸ | GAA | P10253 | 2/20 | 0.67 |
| ▸ | POLB | P06746 | 1/20 | 0.67 |
| ▸ | LMNA | P02545 | 3/20 | 0.66 |
| ▸ | MAPT | P10636 | 3/20 | 0.65 |
| ▸ | NPC1 | O15118 | 2/20 | 0.60 |
| ▸ | RAB9A | P51151 | 2/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 4/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29201497 | 1.00 | CHRNB2 (0.78) | CHRNB2CHRNB4CHRNA3CHRNA4HTT | |
| SCHEMBL1017796 | 0.88 | CHRNB2 (1.00) | CHRNB2CHRNB4CHRNA3CHRNA4HTT | |
| SCHEMBL6300626 | 0.88 | HTT (0.72) | CHRNB2CHRNB4CHRNA3CHRNA4HTT | |
| SCHEMBL6053692 | 0.87 | CYP2C9 (0.78) | CHRNB2CHRNB4CHRNA3CHRNA4ALDH1A1 | |
| Hydrochloric Acid SCHEMBL29598779 | 0.86 | CHRNB2 (0.96) | CHRNB2CHRNB4CHRNA3CHRNA4HTT | |
| SCHEMBL6294961 | 0.84 | HTT (0.60) | CHRNB2CHRNB4CHRNA3CHRNA4HTT | |
| SCHEMBL22820203 | 0.84 | HTT (0.57) | CHRNB2CHRNB4CHRNA3CHRNA4HTT | |
| SCHEMBL2571393 | 0.84 | CHRNB2 (0.78) | CHRNB2CHRNB4CHRNA3CHRNA4HTT | |
| SCHEMBL94735 | 0.84 | CHRNB2 (0.78) | CHRNB2CHRNB4CHRNA3CHRNA4HTT | |
| SCHEMBL7863451 | 0.84 | CHRNB2 (0.78) | CHRNB2CHRNB4CHRNA3CHRNA4HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114835599-B | Preparation method of o-aryl benzamide compound | 绍兴久孚新材料科技有限公司 | 2024-05-03 | — | — | CN | disclosed |
| CN-114835599-A | Preparation method of o-aryl benzamide compound | 绍兴久孚新材料科技有限公司 | 2022-08-02 | — | — | CN | disclosed |