Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.38 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.36 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.36 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.36 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.36 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.36 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.36 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.35 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13430089 | 1.00 | BRD4 (0.39) | BRD4LRRK2ALDH1A1P2RX7GRIN1 | |
| SCHEMBL23999584 | 0.82 | LRRK2 (0.47) | BRD4LRRK2GRIN1GRIN2BGRIN2D | |
| SCHEMBL25045462 | 0.79 | NOTUM (0.40) | BRD4LRRK2ALDH1A1GRIN1GRIN2B | |
| SCHEMBL20639984 | 0.77 | P2RX7 (0.47) | ALDH1A1P2RX7GRIN1GRIN2BGRIN2D | |
| SCHEMBL20168136 | 0.77 | EGLN2 (0.46) | BRD4LRRK2GRIN1GRIN2BKCNJ1 | |
| SCHEMBL30751809 | 0.77 | EGLN2 (0.46) | BRD4LRRK2GRIN1GRIN2BKCNJ1 | |
| SCHEMBL4555166 | 0.76 | CYP1A2 (0.47) | LRRK2ALDH1A1P2RX7GRIN1GRIN2B | |
| SCHEMBL25043785 | 0.76 | GRIN1 (0.40) | BRD4LRRK2GRIN1GRIN2BKCNJ1 | |
| SCHEMBL24135300 | 0.76 | BRD4 (0.40) | BRD4LRRK2ALDH1A1GRIN1GRIN2B | |
| SCHEMBL30445199 | 0.76 | KCNJ1 (0.55) | BRD4LRRK2ALDH1A1P2RX7GRIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114845778-A | Dihydrocyclopentaisoquinoline sulfonamide derivative compound | UCB生物制药有限责任公司 | 2022-08-02 | — | — | CN | disclosed |