Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 1/20 | 0.55 |
| ▸ | LCK | P06239 | 1/20 | 0.52 |
| ▸ | F7 | P08709 | 1/20 | 0.48 |
| ▸ | F3 | P13726 | 1/20 | 0.48 |
| ▸ | SARM1 | Q6SZW1 | 1/20 | 0.48 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.48 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.48 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.48 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.48 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.48 |
| ▸ | SIRT4 | Q9Y6E7 | 1/20 | 0.48 |
| ▸ | HIPK2 | Q9H2X6 | 1/20 | 0.47 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.47 |
| ▸ | AURKA | O14965 | 1/20 | 0.47 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.47 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.47 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.47 |
| ▸ | PAK4 | O96013 | 1/20 | 0.47 |
| ▸ | ABL1 | P00519 | 1/20 | 0.47 |
| ▸ | RET | P07949 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6648425 | 1.00 | AR (0.55) | ARLCKF7F3SARM1 | |
| SCHEMBL29522657 | 0.93 | AR (0.62) | ARLCKF7F3SARM1 | |
| SCHEMBL4280154 | 0.93 | AR (0.62) | ARLCKF7F3SARM1 | |
| SCHEMBL1403704 | 0.83 | MRGPRX4 (0.56) | LCKHIPK2KDRPRKCZSMYD3 | |
| SCHEMBL29488886 | 0.83 | MRGPRX4 (0.56) | LCKHIPK2KDRPRKCZSMYD3 | |
| SCHEMBL7447422 | 0.81 | CYP2A6 (0.55) | LCKHIPK2KDRPRKCZSMYD3 | |
| Hydrochloric Acid SCHEMBL29816771 | 0.81 | MRGPRX4 (0.55) | LCKHIPK2KDRPRKCZSMYD3 | |
| SCHEMBL30134313 | 0.81 | CYP2A6 (0.55) | LCKHIPK2KDRPRKCZSMYD3 | |
| SCHEMBL6984075 | 0.81 | MRGPRX4 (0.55) | LCKHIPK2KDRPRKCZSMYD3 | |
| Potassium SCHEMBL6984080 | 0.81 | MRGPRX4 (0.55) | LCKHIPK2KDRPRKCZSMYD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114845778-A | Dihydrocyclopentaisoquinoline sulfonamide derivative compound | UCB生物制药有限责任公司 | 2022-08-02 | — | — | CN | disclosed |