SCHEMBL29973008

SCHEMBL29973008

FB(F)c1cccc2cc3ccccc3cc12

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.41
KDM4E B2RXH2 4/20 0.41
GAA P10253 3/20 0.41
HSD17B10 Q99714 3/20 0.39
HIF1A Q16665 1/20 0.39
CYP1B1 Q16678 1/20 0.39
KMT2A Q03164 4/20 0.38
MAPT P10636 3/20 0.38
MEN1 O00255 3/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
CYP1A2 P05177 5/20 0.36
ACHE P22303 2/20 0.36
ERBB2 P04626 1/20 0.36
FYN P06241 1/20 0.36
MAOA P21397 1/20 0.36
AHR P35869 1/20 0.36
HPGD P15428 4/20 0.36
GLA P06280 3/20 0.36
NQO2 P16083 1/20 0.34
HTR2A P28223 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1479148 0.84 ALDH1A1 (0.46) ALDH1A1KDM4EGAAHSD17B10HIF1A
SCHEMBL829841 0.78 ALDH1A1 (0.46) ALDH1A1KDM4EGAAHSD17B10HIF1A
SCHEMBL7785169 0.78 ALDH1A1 (0.50) ALDH1A1KDM4EGAAHSD17B10HIF1A
SCHEMBL24012387 0.78 ALDH1A1 (0.41) ALDH1A1KDM4EGAAHSD17B10HIF1A
SCHEMBL14523881 0.78 ALDH1A1 (0.40) ALDH1A1KDM4EGAAHSD17B10HIF1A
SCHEMBL14523872 0.77 ALDH1A1 (0.42) ALDH1A1HSD17B10HIF1AMAPTCYP1A2
SCHEMBL23581506 0.77 ALDH1A1 (0.59) ALDH1A1KDM4EGAAHSD17B10HIF1A
SCHEMBL14523877 0.76 NQO2 (0.43) ALDH1A1KDM4EHSD17B10HIF1AKMT2A
SCHEMBL14523880 0.75 CYP1A2 (0.43) ALDH1A1KDM4EHSD17B10HIF1ACYP1B1
SCHEMBL28715754 0.74 ALDH1A1 (0.47) ALDH1A1KDM4EGAAHSD17B10HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115385941-A Fluoroboropyrrole derivative and preparation method and application thereof 广东工业大学 2022-11-25 CN disclosed