SCHEMBL29973095

CSCC[C@H](NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](CCSC)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](N)CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)O

nearest known ligand 0.57

Predicted protein targets (top 10)

	gene	UniProt	supporting neighbours	confidence
▸	GHSR	Q92847	6/20	0.57

▸	IL23R	Q5VWK5	1/20	0.55

▸	CCKBR	P32239	2/20	0.53

▸	CCKAR	P32238	1/20	0.52

▸	NPY1R	P25929	1/20	0.52

▸	NPY2R	P49146	1/20	0.52

▸	NPY4R	P50391	1/20	0.52

▸	GLP1R	P43220	1/20	0.51

▸	GCGR	P47871	1/20	0.51

▸	GIPR	P48546	1/20	0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL31232428	0.97	GHSR (0.52)	GHSRIL23RCCKBRNPY1RNPY2R
SCHEMBL29419958	0.94	GHSR (0.61)	GHSRNPY1RNPY2RNPY4R
SCHEMBL24172454	0.93	IL23R (0.61)	GHSRIL23RNPY2RGLP1RGCGR
SCHEMBL19731216	0.93	IL23R (0.61)	GHSRIL23RNPY2RGLP1RGCGR
SCHEMBL16692899	0.93	IL23R (0.61)	GHSRIL23RNPY2RGLP1RGCGR
SCHEMBL19731206	0.93	IL23R (0.61)	GHSRIL23RNPY2RGLP1RGCGR
SCHEMBL16692892	0.93	IL23R (0.61)	GHSRIL23RNPY2RGLP1RGCGR
SCHEMBL16692898	0.93	IL23R (0.61)	GHSRIL23RNPY2RGLP1RGCGR
SCHEMBL19731215	0.92	GLP1R (0.61)	GHSRIL23RNPY2RGLP1RGCGR
SCHEMBL31661149	0.92	GHSR (0.61)	GHSR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-4067370-A1	HIGH PENETRATION PRODRUG COMPOSITIONS OF PEPTIDES AND PEPTIDE RELATED COMPOUNDS	Yu, Chongxi (US)	2022-10-05	—	—	EP	disclosed