Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRA | P16234 | 4/20 | 0.61 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.61 |
| ▸ | MET | P08581 | 2/20 | 0.60 |
| ▸ | FGFR2 | P21802 | 6/20 | 0.58 |
| ▸ | KDR | P35968 | 3/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20782675 | 0.88 | ENPP3 (0.53) | PDGFRAPDGFRBMETFGFR2KDR | |
| SCHEMBL20782678 | 0.84 | PDGFRA (0.65) | PDGFRAPDGFRBFGFR2KDR | |
| SCHEMBL30402132 | 0.84 | PDGFRA (0.65) | PDGFRAPDGFRBFGFR2KDR | |
| SCHEMBL4475940 | 0.84 | PDGFRB (0.68) | PDGFRAPDGFRBFGFR2 | |
| SCHEMBL17489327 | 0.81 | PDGFRA (0.68) | PDGFRAPDGFRBFGFR2KDR | |
| SCHEMBL20782493 | 0.81 | FGFR2 (0.68) | PDGFRAPDGFRBFGFR2KDR | |
| SCHEMBL7486400 | 0.80 | FGFR2 (0.84) | PDGFRAPDGFRBFGFR2KDR | |
| SCHEMBL2172904 | 0.80 | PDGFRA (0.64) | PDGFRAPDGFRBMETFGFR2KDR | |
| SCHEMBL167396 | 0.79 | PDGFRA (0.74) | PDGFRAPDGFRBFGFR2KDR | |
| SCHEMBL2176021 | 0.79 | PDGFRA (0.61) | PDGFRAPDGFRBMETFGFR2KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4313048-A1 | PROCESS FOR PREPARATION OF CABOZANTINIB | Biocon Limited (IN) | 2024-02-07 | — | — | EP | disclosed |
| WO-2022201079-A1 | PROCESS FOR PREPARATION OF CABOZANTINIB | BIOCON LIMITED (IN) | 2022-09-29 | — | — | WO | disclosed |