Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 1/20 | 0.52 |
| ▸ | CCR8 | P51685 | 1/20 | 0.52 |
| ▸ | NOS3 | P29474 | 1/20 | 0.44 |
| ▸ | NOS2 | P35228 | 1/20 | 0.44 |
| ▸ | TGFBR1 | P36897 | 9/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CASP6 | P55212 | 1/20 | 0.42 |
| ▸ | TGFBR2 | P37173 | 2/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.39 |
| ▸ | METAP2 | P50579 | 1/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | UBE2N | P61088 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL462761 | 1.00 | CCR1 (0.52) | CCR1CCR8NOS3NOS2TGFBR1 | |
| Hydrochloric Acid SCHEMBL7086071 | 0.98 | CCR1 (0.50) | CCR1CCR8NOS3NOS2TGFBR1 | |
| Hydrochloric Acid SCHEMBL7089446 | 0.98 | CCR1 (0.50) | CCR1CCR8NOS3NOS2TGFBR1 | |
| SCHEMBL8101860 | 0.82 | CCR1 (0.52) | CCR1CCR8NOS3NOS2TGFBR1 | |
| SCHEMBL7086524 | 0.81 | ASIC3 (0.47) | NOS3NOS2POLBKDM4ELMNA | |
| SCHEMBL5687521 | 0.81 | CCR1 (0.50) | CCR1CCR8NOS3NOS2TGFBR1 | |
| SCHEMBL3723641 | 0.79 | CCR1 (0.58) | CCR1CCR8NOS3NOS2TGFBR1 | |
| Hydrochloric Acid SCHEMBL5687740 | 0.79 | CCR1 (0.48) | CCR1CCR8NOS3NOS2TGFBR1 | |
| SCHEMBL7085462 | 0.79 | JAK2 (0.41) | TGFBR1POLBKDM4ELMNACASP1 | |
| SCHEMBL7086276 | 0.79 | MEN1 (0.39) | POLBKDM4ELMNACASP1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117466897-A | Highly selective FGFR2 inhibitors | 深圳福沃药业有限公司 | 2024-01-30 | — | — | CN | disclosed |
| EP-4081199-A2 | LIPOXYGENASE INHIBITORS | SRI International (US) | 2022-11-02 | — | — | EP | disclosed |
| CN-115135316-A | Lipoxygenase inhibitors | 思研（SRI）国际顾问与咨询公司 | 2022-09-30 | — | — | CN | disclosed |