SCHEMBL29973172

SCHEMBL29973172

CSCC[C@H](NC(=O)[C@H](CO)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](N)CO)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](Cc1c[nH]cn1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)N[C@H](C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(=N)N)C(=O)O)C(C)C

nearest known ligand 0.77

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ C5AR1 P21730 2/20 0.77
▸ MC4R P32245 3/20 0.73
▸ MC5R P33032 2/20 0.73
▸ MC3R P41968 2/20 0.73
▸ MC1R Q01726 2/20 0.73
▸ GLP1R P43220 5/20 0.66
▸ GCGR P47871 3/20 0.65
▸ CTSL P07711 3/20 0.64
▸ CTSS P25774 3/20 0.64
▸ CTSK P43235 3/20 0.64
▸ CTSH P09668 1/20 0.64
▸ CXCR4 P61073 3/20 0.60
▸ CXCL8 P10145 1/20 0.59
▸ KEAP1 Q14145 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30017682 0.98 C5AR1 (0.77) C5AR1MC4RMC5RMC3RMC1R
SCHEMBL18388638 0.98 C5AR1 (0.74) C5AR1MC4RMC5RMC3RMC1R
Codactide SCHEMBL29409825 0.98 MC4R (0.74) C5AR1MC4RMC5RMC3RMC1R
SCHEMBL29533861 0.98 C5AR1 (0.74) C5AR1MC4RMC5RMC3RMC1R
SCHEMBL29430238 0.97 MC4R (0.78) C5AR1MC4RMC5RMC3RMC1R
Cosyntropin SCHEMBL522396 0.97 C5AR1 (0.74) C5AR1MC4RMC5RMC3RMC1R
Cosyntropin SCHEMBL29383133 0.97 C5AR1 (0.74) C5AR1MC4RMC5RMC3RMC1R
Cosyntropin SCHEMBL33366 0.97 C5AR1 (0.74) C5AR1MC4RMC5RMC3RMC1R
Cosyntropin SCHEMBL720535 0.97 C5AR1 (0.74) C5AR1MC4RMC5RMC3RMC1R
Cosyntropin SCHEMBL29948667 0.97 C5AR1 (0.74) C5AR1MC4RMC5RMC3RMC1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240307505-A1 DRUG CONTAINING ADRENOCORTICOTROPIC HORMONE OR DERIVATIVE THEREOF AND USE THEREOF ZHANG, JING (CN) 2024-09-19 — — US claimed
EP-4292605-A1 DRUG CONTAINING ADRENOCORTICOTROPIC HORMONE OR DERIVATIVE THEREOF AND USE THEREOF Zhang, Jing (CN) 2023-12-20 — — EP claimed
WO-2022206716-A1 DRUG CONTAINING ADRENOCORTICOTROPIC HORMONE OR DERIVATIVE THEREOF AND USE THEREOF 张菁 2022-10-06 — — WO claimed
CN-115137809-A Medicine containing adrenocorticotropic hormone and its derivative and its use 张菁 2022-10-04 — — CN claimed
US-20240309065-A1 SHORT APOC-II MIMETIC PEPTIDES AND METHODS OF USE THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPT. OF HEALTH AND HUMAN SERVICES (US) 2024-09-19 — — US disclosed
US-20240307505-A1 DRUG CONTAINING ADRENOCORTICOTROPIC HORMONE OR DERIVATIVE THEREOF AND USE THEREOF ZHANG, JING (CN) 2024-09-19 — — US disclosed
US-20240165127-A1 CONTRAST AGENT FOR DIAGNOSIS OF VASCULAR DISEASE CONTAINING GADOLINIUM-BASED COMPOUND AS ACTIVE INGREDIENT AND SYNTHESIS METHOD THEREFOR DAEGU CATHOLIC UNIVERSITY INDUSTRY ACADEMIC COOPERATION FOUNDATION (KR) 2024-05-23 — — US disclosed
EP-4359432-A2 SHORT APOC-II MIMETIC PEPTIDES AND METHODS OF USE The United States of America, as represented by The Secretary, Department of Health and Human Services (US) 2024-05-01 — — EP disclosed
CN-117580857-A APOC-II short mimetic peptides and methods of use 美国政府(由卫生和人类服务部的部长所代表) 2024-02-20 — — CN disclosed
EP-4292605-A1 DRUG CONTAINING ADRENOCORTICOTROPIC HORMONE OR DERIVATIVE THEREOF AND USE THEREOF Zhang, Jing (CN) 2023-12-20 — — EP disclosed
US-11821902-B2 Quantitative peptide or protein assay PIERCE BIOTECHNOLOGY, INC. (US) 2023-11-21 — — US disclosed
WO-2022271814-A2 SHORT APOC-II MIMETIC PEPTIDES AND METHODS OF USE THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 2022-12-29 — — WO disclosed
WO-2022206716-A1 DRUG CONTAINING ADRENOCORTICOTROPIC HORMONE OR DERIVATIVE THEREOF AND USE THEREOF 张菁 2022-10-06 — — WO disclosed
EP-4067370-A1 HIGH PENETRATION PRODRUG COMPOSITIONS OF PEPTIDES AND PEPTIDE RELATED COMPOUNDS Yu, Chongxi (US) 2022-10-05 — — EP disclosed
CN-115137809-A Medicine containing adrenocorticotropic hormone and its derivative and its use 张菁 2022-10-04 — — CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240165127-A1 CONTRAST AGENT FOR DIAGNOSIS OF VASCULAR DISEASE CONTAINING GADOLINIUM-BASED COMPOUND AS ACTIVE INGREDIENT AND SYNTHESIS METHOD THEREFOR CTRL, CELA1, PRSS1 C5AR1 474/4885MC4R 4088/4885MC5R 4667/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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