Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPO | P05164 | 1/20 | 0.49 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | BACE1 | P56817 | 1/20 | 0.40 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.40 |
| ▸ | ADCY10 | Q96PN6 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sampirtine SCHEMBL1230637 | 1.00 | MPO (0.49) | MPOIDO1BACE1LOXL2ADCY10 | |
| Sampirtine SCHEMBL10569152 | 0.98 | MPO (0.48) | MPOIDO1BACE1LOXL2ADCY10 | |
| Sampirtine SCHEMBL10569379 | 0.86 | KDM4E (0.42) | MPO | |
| SCHEMBL21223703 | 0.81 | MPO (0.49) | MPOADCY10 | |
| SCHEMBL57463 | 0.80 | MPO (0.56) | MPOADCY10 | |
| SCHEMBL21223649 | 0.80 | CYP3A4 (0.46) | MPO | |
| SCHEMBL10569673 | 0.79 | MPO (0.55) | MPOIDO1ADCY10 | |
| Hydrochloric Acid SCHEMBL21223749 | 0.78 | CYP3A4 (0.45) | MPO | |
| Hydrochloric Acid SCHEMBL10569158 | 0.78 | MPO (0.53) | MPOIDO1ADCY10 | |
| SCHEMBL10573978 | 0.73 | MPO (0.51) | MPOIDO1ADCY10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4081199-A2 | LIPOXYGENASE INHIBITORS | SRI International (US) | 2022-11-02 | — | — | EP | disclosed |
| CN-115135316-A | Lipoxygenase inhibitors | 思研（SRI）国际顾问与咨询公司 | 2022-09-30 | — | — | CN | disclosed |