SCHEMBL29973251

SCHEMBL29973251

CCCCc1cccc(Cc2noc(CC(C(=O)OC(C)(C)C)P(=O)(OCC)OCC)n2)c1

nearest known ligand 0.39

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39
LMNA P02545 2/20 0.39
PPARG P37231 4/20 0.34
PPARA Q07869 4/20 0.34
APLNR P35414 2/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
KDM4E B2RXH2 1/20 0.33
HMGCR P04035 1/20 0.31
ZAP70 P43403 2/20 0.31
TLR8 Q9NR97 1/20 0.31
MAOA P21397 1/20 0.31
S1PR4 O95977 1/20 0.31
S1PR1 P21453 1/20 0.31
S1PR3 Q99500 1/20 0.31
S1PR5 Q9H228 1/20 0.31
SRC P12931 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23578518 1.00 MEN1 (0.39) MEN1KMT2ALMNAPPARGPPARA
SCHEMBL25801818 0.92 MEN1 (0.40) MEN1KMT2ALMNAPPARGPPARA
SCHEMBL23578163 0.91 MEN1 (0.33) MEN1KMT2ALMNAPPARGPPARA
SCHEMBL25804866 0.89 SRC (0.34) MEN1KMT2AS1PR4S1PR1S1PR3
SCHEMBL25804839 0.86 SPHK2 (0.39) KMT2ALMNA
SCHEMBL25805969 0.86 MEN1 (0.33) MEN1KMT2ALMNAL3MBTL1KDM4E
SCHEMBL23578353 0.85 ZAP70 (0.41) MEN1KMT2ALMNAL3MBTL1HMGCR
SCHEMBL29973065 0.85 ZAP70 (0.41) MEN1KMT2ALMNAL3MBTL1HMGCR
SCHEMBL23588100 0.84 MAPT (0.37) LMNAKDM4EZAP70S1PR4S1PR1
SCHEMBL23578202 0.84 TP53 (0.32) PPARGPPARAAPLNRHMGCRS1PR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4081511-B3 CARBOXY DERIVATIVES WITH ANTIINFLAMMATORY PROPERTIES SITRYX THERAPEUTICS LTD (GB) 2026-03-04 EP disclosed
EP-4081511-A1 CARBOXY DERIVATIVES WITH ANTIINFLAMMATORY PROPERTIES Sitryx Therapeutics Limited (GB) 2022-11-02 EP disclosed