SCHEMBL29973065

SCHEMBL29973065

CCOP(=O)(OCC)C(Cc1nc(Cc2ccc3ccccc3c2)no1)C(=O)OC(C)(C)C

nearest known ligand 0.41

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ZAP70 P43403 6/20 0.41
SRC P12931 3/20 0.41
EPHX2 P34913 2/20 0.40
MEN1 O00255 1/20 0.37
KMT2A Q03164 1/20 0.37
LMNA P02545 2/20 0.37
CTSB P07858 1/20 0.35
CTSS P25774 1/20 0.35
CTSK P43235 1/20 0.35
PSMB5 P28074 2/20 0.34
TSHR P16473 1/20 0.34
MAPK1 P28482 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
HMGCR P04035 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23578353 1.00 ZAP70 (0.41) ZAP70SRCEPHX2MEN1KMT2A
SCHEMBL25801760 0.92 ZAP70 (0.41) ZAP70SRCEPHX2MEN1KMT2A
SCHEMBL29973479 0.88 TSHR (0.44) ZAP70SRCMEN1KMT2ALMNA
SCHEMBL23578557 0.88 TSHR (0.44) ZAP70SRCMEN1KMT2ALMNA
SCHEMBL25804590 0.86 KMT2A (0.35) ZAP70SRCEPHX2MEN1KMT2A
SCHEMBL23578356 0.86 MEN1 (0.33) ZAP70SRCMEN1KMT2ALMNA
SCHEMBL23588157 0.86 MAPT (0.41) ZAP70SRCMEN1KMT2ALMNA
SCHEMBL25805969 0.86 MEN1 (0.33) ZAP70SRCMEN1KMT2ALMNA
SCHEMBL25804329 0.86 MAPT (0.41) ZAP70SRCMEN1KMT2ALMNA
SCHEMBL29973251 0.85 MEN1 (0.39) ZAP70SRCMEN1KMT2ALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4081511-B3 CARBOXY DERIVATIVES WITH ANTIINFLAMMATORY PROPERTIES SITRYX THERAPEUTICS LTD (GB) 2026-03-04 EP disclosed
EP-4081511-A1 CARBOXY DERIVATIVES WITH ANTIINFLAMMATORY PROPERTIES Sitryx Therapeutics Limited (GB) 2022-11-02 EP disclosed