Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 1/20 | 0.52 |
| ▸ | THRA | P10827 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | SMPD1 | P17405 | 4/20 | 0.44 |
| ▸ | PDE4A | P27815 | 1/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.43 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23578191 | 1.00 | BACE1 (0.52) | BACE1THRATHRBGLASMN1; SMN2 | |
| SCHEMBL4239925 | 0.96 | THRA (0.54) | BACE1THRATHRBGLASMN1; SMN2 | |
| SCHEMBL13139447 | 0.94 | THRA (0.56) | BACE1THRATHRBGLASMN1; SMN2 | |
| SCHEMBL23578085 | 0.93 | CSNK2A1 (0.50) | BACE1THRATHRBGLASMN1; SMN2 | |
| SCHEMBL25801629 | 0.84 | THRA (0.48) | THRATHRBSMN1; SMN2SMPD1 | |
| SCHEMBL29973327 | 0.83 | THRA (0.49) | THRATHRBSMN1; SMN2SMPD1 | |
| SCHEMBL23578552 | 0.83 | THRA (0.49) | THRATHRBSMN1; SMN2SMPD1 | |
| SCHEMBL23588051 | 0.80 | THRA (0.52) | THRATHRBSMN1; SMN2SMPD1 | |
| SCHEMBL13139467 | 0.79 | THRA (0.57) | THRATHRBSMN1; SMN2ALDH1A1SMPD1 | |
| SCHEMBL13139448 | 0.79 | THRA (0.55) | THRATHRBALDH1A1SMPD1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4081511-A1 | CARBOXY DERIVATIVES WITH ANTIINFLAMMATORY PROPERTIES | Sitryx Therapeutics Limited (GB) | 2022-11-02 | — | — | EP | disclosed |