Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | ZAP70 | P43403 | 7/20 | 0.38 |
| ▸ | SRC | P12931 | 5/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | CRHBP | P24387 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | NR1I3 | Q14994 | 1/20 | 0.35 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.35 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.35 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.35 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23578299 | 1.00 | TSHR (0.51) | TSHRMAPK1TDP1ZAP70SRC | |
| SCHEMBL23578197 | 0.88 | MAPT (0.47) | TSHRMAPK1TDP1L3MBTL1ALOX15 | |
| SCHEMBL25801776 | 0.86 | MAPT (0.35) | TSHRMAPK1TDP1L3MBTL1MAPT | |
| SCHEMBL23588107 | 0.85 | MAPT (0.45) | TSHRMAPK1TDP1L3MBTL1ALOX15 | |
| SCHEMBL23578293 | 0.85 | TSHR (0.38) | TSHRMAPK1TDP1ZAP70SRC | |
| SCHEMBL29973191 | 0.85 | TSHR (0.38) | TSHRMAPK1TDP1ZAP70SRC | |
| SCHEMBL23578414 | 0.84 | TP53 (0.38) | TSHRMAPK1TDP1MAPTALDH1A1 | |
| SCHEMBL23578571 | 0.84 | MAPT (0.35) | TSHRMAPK1TDP1L3MBTL1MAPT | |
| SCHEMBL23588088 | 0.83 | TSHR (0.62) | TSHRMAPK1TDP1ZAP70SRC | |
| SCHEMBL29844162 | 0.83 | TSHR (0.62) | TSHRMAPK1TDP1ZAP70SRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4081511-A1 | CARBOXY DERIVATIVES WITH ANTIINFLAMMATORY PROPERTIES | Sitryx Therapeutics Limited (GB) | 2022-11-02 | — | — | EP | disclosed |