SCHEMBL23578414

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL23578154	0.91	MEN1 (0.40)	EGLN1KMT2AMEN1
	SCHEMBL23578571	0.89	MAPT (0.35)	MAPTTSHRALDH1A1HDAC6KMT2A
	SCHEMBL23578197	0.89	MAPT (0.47)	NPC1RAB9ASMN1; SMN2MAPTTSHR
	SCHEMBL25801971	0.88	MAPT (0.35)	MAPTTSHRALDH1A1HDAC6KMT2A
	SCHEMBL23588094	0.86	TP53 (0.40)	TP53NPC1CYP1A2CYP2C19CYP2C9
	SCHEMBL25801788	0.86	ALDH1A1 (0.36)	TP53NPC1RAB9ASMN1; SMN2MAPT
	SCHEMBL23588107	0.86	MAPT (0.45)	NPC1RAB9ASMN1; SMN2MAPTTSHR
	SCHEMBL23578363	0.85	KMT2A (0.35)	MAPTTSHRALDH1A1HDAC6KMT2A
	SCHEMBL23578189	0.85	MAPT (0.38)	MAPTKMT2APPARGPPARDPPARA
	SCHEMBL25801811	0.85	ALDH1A1 (0.37)	ALDH1A1KMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.