Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN11 | Q06124 | 6/20 | 0.34 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HCRTR1 | O43613 | 4/20 | 0.33 |
| ▸ | HCRTR2 | O43614 | 4/20 | 0.33 |
| ▸ | CKS1B | P61024 | 1/20 | 0.32 |
| ▸ | SKP1 | P63208 | 1/20 | 0.32 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.32 |
| ▸ | HTR3A | P46098 | 1/20 | 0.32 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.31 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.30 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL23045212 | 0.99 | PTPN11 (0.34) | PTPN11MAPK3MAPK1HCRTR1HCRTR2 | |
| Hydrochloric Acid SCHEMBL23045209 | 0.82 | MAPT (0.35) | HCRTR1HCRTR2CKS1BSKP1SKP2 | |
| SCHEMBL23055431 | 0.76 | GRIN2B (0.38) | PTPN11MAPK3MAPK1HCRTR1HCRTR2 | |
| SCHEMBL23055428 | 0.73 | KDM4E (0.36) | CKS1BSKP1SKP2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL23045211 | 0.67 | JAK2 (0.34) | ALDH1A1HSD17B10 | |
| SCHEMBL23045224 | 0.66 | CCR4 (0.32) | — | |
| Hydrochloric Acid SCHEMBL23045210 | 0.64 | MAPT (0.38) | ALDH1A1HPGD | |
| SCHEMBL20180620 | 0.60 | KCNH2 (0.41) | PTPN11CYP11B1CYP11B2 | |
| SCHEMBL23055669 | 0.59 | GRIN2B (0.39) | CKS1BSKP1SKP2ALDH1A1HCAR2 | |
| Hydrochloric Acid SCHEMBL28926964 | 0.59 | GRIN2B (0.38) | CKS1BSKP1SKP2ALDH1A1HCAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115397467-A | Therapeutic agent for tauopathy | 住友制药株式会社 | 2022-11-25 | — | — | CN | disclosed |