Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 3/20 | 0.39 |
| ▸ | CHRNE | Q04844 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
| ▸ | CDK2 | P24941 | 1/20 | 0.36 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.35 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.35 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3884626 | 1.00 | NOTUM (0.40) | NOTUMBRD4CHRNEPKMPARP1 | |
| SCHEMBL3502666 | 0.89 | CHRNE (0.41) | BRD4CHRNEPKMBCHE | |
| SCHEMBL14234870 | 0.85 | CDK2 (0.44) | NOTUMBRD4PKMPARP1CDK2 | |
| SCHEMBL1881886 | 0.82 | CDK2 (0.38) | NOTUMBRD4PKMPARP1CDK2 | |
| SCHEMBL4999700 | 0.81 | PNMT (0.41) | NOTUMBRD4PKMPARP1BCHE | |
| SCHEMBL5542232 | 0.81 | NOTUM (0.44) | NOTUMBRD4PARP1PARP10PARP11 | |
| SCHEMBL22175660 | 0.81 | NOTUM (0.40) | NOTUMBRD4PKMPARP1PARP10 | |
| SCHEMBL5535553 | 0.81 | NOTUM (0.40) | NOTUMBRD4PKMPARP1PARP10 | |
| SCHEMBL27939286 | 0.79 | AKR1B1 (0.43) | NOTUMBRD4PKMPARP1 | |
| SCHEMBL24654698 | 0.78 | NOTUM (0.38) | NOTUMBRD4PKMCDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113227054-B | ROCK kinase inhibitors | 切尔韦洛治疗有限责任公司 | 2025-04-11 | — | — | CN | disclosed |
| EP-4426681-A1 | PHTHALAZINE DERIVATIVES AS PYRUVATE KINASE MODULATORS | Sitryx Therapeutics Limited (GB) | 2024-09-11 | — | — | EP | disclosed |
| WO-2023079294-A1 | PHTHALAZINE DERIVATIVES AS PYRUVATE KINASE MODULATORS | SITRYX THERAPEUTICS LIMITED (GB) | 2023-05-11 | — | — | WO | disclosed |
| CN-115397467-A | Therapeutic agent for tauopathy | 住友制药株式会社 | 2022-11-25 | — | — | CN | disclosed |