SCHEMBL2997425

SCHEMBL2997425

CCCCCC1CCOC(CCCCC)O1

nearest known ligand 0.62

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 1/20 0.62
ALDH1A1 P00352 1/20 0.55
PRKD3 O94806 2/20 0.48
PRKCG P05129 2/20 0.48
PRKCB P05771 2/20 0.48
PRKCA P17252 2/20 0.48
PRKCH P24723 2/20 0.48
PRKCI P41743 2/20 0.48
PRKCE Q02156 2/20 0.48
PRKCQ Q04759 2/20 0.48
PRKCZ Q05513 2/20 0.48
PRKCD Q05655 2/20 0.48
PRKD1 Q15139 2/20 0.48
ENPP2 Q13822 13/20 0.46
LPAR2 Q9HBW0 8/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7674359 0.94 EPHX1 (0.60) EPHX1ALDH1A1PRKD3PRKCGPRKCB
SCHEMBL28218988 0.91 EPHX1 (0.55) EPHX1ALDH1A1PRKD3PRKCGPRKCB
SCHEMBL7678863 0.91 EPHX1 (0.60) EPHX1ALDH1A1PRKD3PRKCGPRKCB
SCHEMBL7764030 0.90 EPHX1 (0.55) EPHX1ALDH1A1PRKD3PRKCGPRKCB
SCHEMBL7760388 0.87 EPHX1 (0.56) EPHX1ALDH1A1PRKD3PRKCGPRKCB
SCHEMBL28212337 0.83 EPHX1 (0.47) EPHX1ALDH1A1PRKD3PRKCGPRKCB
SCHEMBL7764100 0.82 EPHX1 (0.46) EPHX1ALDH1A1PRKD3PRKCGPRKCB
SCHEMBL7764093 0.82 EPHX1 (0.46) EPHX1ALDH1A1PRKD3PRKCGPRKCB
SCHEMBL7832019 0.82 ALDH1A1 (0.68) EPHX1ALDH1A1PRKD3PRKCGPRKCB
SCHEMBL7678940 0.81 EPHX1 (0.62) EPHX1ALDH1A1PRKD3PRKCGPRKCB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240277012-A1 DUPLICATE BEVERAGE WANG JIE (US) 2024-08-22 US disclosed
CN-118076767-A Method and formulation for producing an optical metal oxide layer 默克专利有限公司 2024-05-24 CN disclosed
WO-2023057401-A1 METHOD AND FORMULATION FOR PREPARING OPTICAL METAL OXIDE LAYERS MERCK PATENT GMBH (DE) 2023-04-13 WO disclosed
US-20160193179-A1 Treatment of Cardiovascular Risk in Diabetic Patients SAKARIASSEN KJELL STEINAR (IT) 2016-07-07 US disclosed
WO-2015193630-A1 TREATMENT OF CARDIOVASCULAR RISK IN PATIENTS WITH CARDIOVASCULAR DISEASE AND/OR DIABETES EVOLVA SA (CH) 2015-12-23 WO disclosed
EP-2934513-A2 TREATMENT OF CARDIOVASCULAR RISK IN DIABETIC PATIENTS Evolva SA (CH) 2015-10-28 EP disclosed
US-20150158838-A1 Prodrugs of Substituted 1,3-Dioxanes and Their Uses EVOLVA SA (CH) 2015-06-11 US disclosed
US-8952053-B2 Prodrugs of substituted 1,3-dioxanes and their uses EVOLVA SA (CH) 2015-02-10 US disclosed
WO-2014106775-A2 TREATMENT OF CARDIOVASCULAR RISK IN DIABETIC PATIENTS EVOLVA SA (CH) 2014-07-10 WO disclosed
US-20130253045-A1 Prodrugs of Substituted 1,3-Dioxanes and Their Uses EVOLVA SA (CH) 2013-09-26 US disclosed
US-8486994-B2 Prodrugs of substituted 1,3-dioxanes and their uses EVOLVA SA (CH) 2013-07-16 US disclosed
US-20100087517-A1 PRODRUGS OF SUBSTITUTED 1,3-DIOXANES AND THEIR USES EVOLVA SA (CH) 2010-04-08 US disclosed
EP-2120567-A1 PRODRUGS OF SUBSTITUTED 1,3-DIOXANES AND THEIR USES Evolva SA (CH) 2009-11-25 EP disclosed
WO-2008089464-A1 PRODRUGS OF SUBSTITUTED 1,3-DIOXANES AND THEIR USES EVOLVA SA (CH) 2008-07-24 WO disclosed
EP-1021433-B1 METHOD FOR PRODUCING NATURAL DIOL-1,3 DERIVATIVES AND CORRESPONDING NATURAL 1,3-DIOXANE DERIVATIVES PERNOD RICARD (FR) 2001-11-14 EP disclosed
EP-0927176-B1 1,3-DIOXANE DERIVATIVES, SYNTHESIS METHOD THEREFOR AND AROMATIC COMPOSITIONS CONTAINING SAME PERNOD RICARD (FR) 2001-05-30 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160193179-A1 Treatment of Cardiovascular Risk in Diabetic Patients P2RY12, P2RY13, P2RY6 EPHX1 129/4885ALDH1A1 447/4885PRKD3 1822/4885
US-20100087517-A1 PRODRUGS OF SUBSTITUTED 1,3-DIOXANES AND THEIR USES TBXA2R, PPARG, PPARA EPHX1 344/4885ALDH1A1 440/4885PRKD3 1249/4885
US-20130253045-A1 Prodrugs of Substituted 1,3-Dioxanes and Their Uses TBXA2R, PPARG, PPARA EPHX1 344/4885ALDH1A1 440/4885PRKD3 1249/4885
US-20150158838-A1 Prodrugs of Substituted 1,3-Dioxanes and Their Uses TBXA2R, PPARG, PPARA EPHX1 344/4885ALDH1A1 440/4885PRKD3 1249/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.