SCHEMBL29974376

SCHEMBL29974376

C=CC(=O)OCC[N+](C)(CCCCCCCC)CCCCCCCCCCCC

nearest known ligand 0.61

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
TSHR P16473 9/20 0.61
HPGD P15428 1/20 0.61
ALDH1A1 P00352 3/20 0.52
CYP3A4 P08684 1/20 0.52
TP53 P04637 2/20 0.43
HIF1A Q16665 2/20 0.43
HSD17B10 Q99714 1/20 0.43
HCAR2 Q8TDS4 3/20 0.42
ATM Q13315 1/20 0.42
ACHE P22303 3/20 0.41
THRB P10828 3/20 0.41
RAD52 P43351 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39
THRA P10827 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29106977 0.98 TSHR (0.59) TSHRHPGDALDH1A1CYP3A4TP53
SCHEMBL29107051 0.94 TSHR (0.57) TSHRHPGDALDH1A1CYP3A4TP53
SCHEMBL13719604 0.93 TSHR (0.65) TSHRHPGDALDH1A1CYP3A4TP53
Bromide SCHEMBL29125664 0.92 TSHR (0.56) TSHRHPGDALDH1A1CYP3A4TP53
Hydrochloric Acid SCHEMBL29078785 0.92 TSHR (0.56) TSHRHPGDALDH1A1CYP3A4TP53
Bromide SCHEMBL30490647 0.92 TSHR (0.56) TSHRHPGDALDH1A1CYP3A4TP53
Hydrochloric Acid SCHEMBL28340565 0.92 TSHR (0.56) TSHRHPGDALDH1A1CYP3A4TP53
SCHEMBL5693523 0.87 TSHR (0.61) TSHRHPGDALDH1A1CYP3A4TP53
SCHEMBL9480136 0.87 TSHR (0.61) TSHRHPGDALDH1A1CYP3A4TP53
SCHEMBL9485642 0.87 TSHR (0.61) TSHRHPGDALDH1A1CYP3A4TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022209538-A1 FLUORINE-BASED IONIC LIQUID AND PRODUCTION METHOD THEREOF 第一工業製薬株式会社 2022-10-06 WO disclosed