Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 3/20 | 0.41 |
| ▸ | CHRM1 known ✓ | P11229 | 2/20 | 0.39 |
| ▸ | CHRM3 known ✓ | P20309 | 2/20 | 0.39 |
| ▸ | CHRM2 known ✓ | P08172 | 1/20 | 0.39 |
| ▸ | CHRM4 known ✓ | P08173 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 6/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | HCAR2 | Q8TDS4 | 3/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | MLNR | O43193 | 1/20 | 0.39 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.39 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.39 |
| ▸ | PGR | P06401 | 1/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.39 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL30490647 | 1.00 | TSHR (0.56) | TSHRHPGDALDH1A1CYP3A4HCAR2 | |
| SCHEMBL29107051 | 0.98 | TSHR (0.57) | TSHRHPGDALDH1A1CYP3A4HCAR2 | |
| Hydrochloric Acid SCHEMBL29078785 | 0.97 | TSHR (0.56) | TSHRHPGDALDH1A1CYP3A4HCAR2 | |
| Hydrochloric Acid SCHEMBL28340565 | 0.97 | TSHR (0.56) | TSHRHPGDALDH1A1CYP3A4HCAR2 | |
| SCHEMBL29974376 | 0.92 | TSHR (0.61) | TSHRHPGDALDH1A1CYP3A4HCAR2 | |
| SCHEMBL29106977 | 0.91 | TSHR (0.59) | TSHRHPGDALDH1A1CYP3A4HCAR2 | |
| SCHEMBL13719604 | 0.86 | TSHR (0.65) | TSHRHPGDALDH1A1CYP3A4HCAR2 | |
| Bromide SCHEMBL3630565 | 0.85 | TSHR (0.59) | TSHRHPGDALDH1A1CYP3A4HCAR2 | |
| Bromide SCHEMBL1867369 | 0.85 | TSHR (0.59) | TSHRHPGDALDH1A1CYP3A4HCAR2 | |
| Bromide SCHEMBL8196037 | 0.85 | TSHR (0.59) | TSHRHPGDALDH1A1CYP3A4HCAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117247090-A | Sewage antibacterial corrosion inhibitor for oil field and preparation method thereof | 辛集市鑫顺通化工有限公司 | 2023-12-19 | — | — | CN | disclosed |