Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EIF4A3 | P38919 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | NOS2 | P35228 | 5/20 | 0.33 |
| ▸ | GRIN2D | O15399 | 3/20 | 0.32 |
| ▸ | GRIN3B | O60391 | 3/20 | 0.32 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.32 |
| ▸ | GRIN2A | Q12879 | 3/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.32 |
| ▸ | GRIN2C | Q14957 | 3/20 | 0.32 |
| ▸ | GRIN3A | Q8TCU5 | 3/20 | 0.32 |
| ▸ | NOS3 | P29474 | 4/20 | 0.31 |
| ▸ | NOS1 | P29475 | 4/20 | 0.31 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.31 |
| ▸ | DAO | P14920 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27164027 | 1.00 | EIF4A3 (0.42) | EIF4A3MAPTARKDM4ENOS2 | |
| SCHEMBL25989272 | 0.85 | MEN1 (0.39) | EIF4A3MAPTARKDM4ENOS2 | |
| SCHEMBL9775929 | 0.79 | EIF4A3 (0.41) | EIF4A3MAPTARKDM4ENOS2 | |
| SCHEMBL29388927 | 0.78 | IDH1 (0.36) | EIF4A3MAPTKDM4EGRIN2DGRIN3B | |
| SCHEMBL16637455 | 0.78 | IDH1 (0.36) | EIF4A3MAPTKDM4EGRIN2DGRIN3B | |
| SCHEMBL24717492 | 0.76 | ALDH1A1 (0.35) | EIF4A3MAPTKDM4EGRIN2DGRIN3B | |
| SCHEMBL30077845 | 0.76 | F2 (0.34) | EIF4A3 | |
| SCHEMBL18128491 | 0.76 | F2 (0.34) | EIF4A3 | |
| SCHEMBL29153580 | 0.73 | EIF4A3 (0.30) | EIF4A3 | |
| SCHEMBL25433555 | 0.71 | MAPT (0.38) | MAPTARKDM4EGRIN2DGRIN3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4329888-A1 | 2-AMINOBENZOTHIAZOLE COMPOUNDS AND METHODS OF USE THEREOF | Amgen Inc. (US) | 2024-03-06 | — | — | EP | disclosed |
| CN-117651700-A | 2-aminobenzothiazole compounds and methods of use | 安进公司 | 2024-03-05 | — | — | CN | disclosed |
| WO-2022232332-A1 | 2-AMINOBENZOTHIAZOLE COMPOUNDS AND METHODS OF USE THEREOF | AMGEN INC. (US) | 2022-11-03 | — | — | WO | disclosed |