Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.31 |
| ▸ | JAK2 | O60674 | 1/20 | 0.31 |
| ▸ | JAK1 | P23458 | 1/20 | 0.31 |
| ▸ | TYK2 | P29597 | 1/20 | 0.31 |
| ▸ | JAK3 | P52333 | 1/20 | 0.31 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.30 |
| ▸ | BRD4 | O60885 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5492557 | 0.85 | FEN1 (0.31) | BRD4 | |
| SCHEMBL28852542 | 0.71 | IDH1 (0.39) | — | |
| SCHEMBL29974960 | 0.71 | IDH1 (0.39) | — | |
| SCHEMBL23612076 | 0.71 | JAK2 (0.30) | JAK2JAK1TYK2JAK3 | |
| Hydrochloric Acid SCHEMBL28266713 | 0.70 | HRH3 (0.46) | PIK3CA | |
| Ammonia Solution, Strong SCHEMBL16914060 | 0.68 | HTT (0.46) | JAK2JAK1TYK2JAK3 | |
| SCHEMBL20554028 | 0.68 | PRKCZ (0.37) | — | |
| SCHEMBL23363892 | 0.66 | TEAD2 (0.38) | PIK3CABRD4 | |
| SCHEMBL23612192 | 0.66 | JAK2 (0.33) | JAK2JAK1TYK2JAK3 | |
| SCHEMBL29988592 | 0.66 | JAK2 (0.33) | JAK2JAK1TYK2JAK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115135316-A | Lipoxygenase inhibitors | 思研（SRI）国际顾问与咨询公司 | 2022-09-30 | — | — | CN | disclosed |