Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDPK1 | O15530 | 1/20 | 0.67 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.44 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.41 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.40 |
| ▸ | PLAU | P00749 | 1/20 | 0.40 |
| ▸ | C1S | P09871 | 1/20 | 0.40 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.40 |
| ▸ | SRC | P12931 | 2/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.39 |
| ▸ | GABRP | O00591 | 2/20 | 0.38 |
| ▸ | GABRD | O14764 | 2/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.38 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.38 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.38 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.38 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.38 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Isoquinolin-3-Amine SCHEMBL28186686 | 1.00 | PDPK1 (0.67) | PDPK1PAX8CDK5CDK5R1L3MBTL1 | |
| Isoquinolin-3-Amine SCHEMBL30378027 | 0.82 | PDPK1 (1.00) | PDPK1PLAUFGFR1SRCCYP1A2 | |
| Isoquinolin-3-Amine SCHEMBL177520 | 0.82 | PDPK1 (1.00) | PDPK1PLAUFGFR1SRCCYP1A2 | |
| Isoquinolin-3-Amine SCHEMBL29975748 | 0.82 | PDPK1 (1.00) | PDPK1PLAUFGFR1SRCCYP1A2 | |
| Trifluoroacetic Acid SCHEMBL1658081 | 0.80 | EGLN1 (0.47) | PAX8L3MBTL1GABRPGABRDGABRA1 | |
| Isoquinolin-3-Amine SCHEMBL28187424 | 0.80 | PDPK1 (0.95) | PDPK1PLAUFGFR1SRCCYP1A2 | |
| Anthracene SCHEMBL1558998 | 0.78 | CES1 (0.50) | PAX8L3MBTL1IDO1CYP1A2 | |
| Trifluoroacetic Acid SCHEMBL5106724 | 0.78 | EGLN1 (0.45) | PDPK1PAX8L3MBTL1CYP1A2CYP2A6 | |
| Trifluoroacetic Acid SCHEMBL27827825 | 0.77 | ALDH1A1 (0.50) | NPC1MGAM | |
| Phthalazine SCHEMBL28331232 | 0.76 | CES1 (0.45) | PAX8L3MBTL1C1SCYP1A2MGAM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4329757-A1 | HETEROCYCLIC COMPOUNDS AND METHODS OF USE | Amgen Inc. (US) | 2024-03-06 | — | — | EP | disclosed |
| WO-2022232331-A1 | HETEROCYCLIC COMPOUNDS AND METHODS OF USE | AMGEN INC. (US) | 2022-11-03 | — | — | WO | disclosed |