Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 11/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.60 |
| ▸ | HPGD | P15428 | 5/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.60 |
| ▸ | SDHB | P21912 | 4/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.60 |
| ▸ | HTT | P42858 | 2/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.60 |
| ▸ | NPC1 | O15118 | 1/20 | 0.60 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | TP53 | P04637 | 1/20 | 0.60 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.60 |
| ▸ | RAB9A | P51151 | 1/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.60 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.54 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19805733 | 1.00 | KDM4E (0.60) | KDM4EALDH1A1HPGDHSD17B10SDHB | |
| SCHEMBL31314434 | 0.81 | KDM4E (0.60) | KDM4EALDH1A1HPGDHSD17B10SDHB | |
| SCHEMBL19805734 | 0.78 | KDM4E (0.60) | KDM4EALDH1A1HPGDHSD17B10SDHB | |
| SCHEMBL29976623 | 0.78 | KDM4E (0.60) | KDM4EALDH1A1HPGDHSD17B10SDHB | |
| SCHEMBL19805731 | 0.76 | KDM4E (0.57) | KDM4EALDH1A1HPGDHSD17B10SDHB | |
| SCHEMBL29976376 | 0.76 | KDM4E (0.57) | KDM4EALDH1A1HPGDHSD17B10SDHB | |
| SCHEMBL21019805 | 0.76 | SDHB (1.00) | KDM4EALDH1A1HPGDHSD17B10SDHB | |
| SCHEMBL19805735 | 0.75 | KDM4E (0.66) | KDM4EALDH1A1HPGDHSD17B10SDHB | |
| SCHEMBL19805902 | 0.75 | KDM4E (0.56) | KDM4EALDH1A1HPGDHSD17B10SDHB | |
| SCHEMBL19805808 | 0.74 | SDHB (1.00) | KDM4EALDH1A1HPGDHSD17B10SDHB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110023292-B | Apoptosis inhibitors | 北京生命科学研究所 | 2022-10-04 | — | — | CN | disclosed |