SCHEMBL29975893

SCHEMBL29975893

COCOc1cc2cc(C(=O)CC(=O)OC(C)(C)C)sc2cc1OC

nearest known ligand 0.69

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ STING1 Q86WV6 12/20 0.69
▸ ACHE P22303 8/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25692521 1.00 STING1 (0.69) STING1ACHE
SCHEMBL20022296 0.92 STING1 (0.81) STING1ACHE
SCHEMBL25693665 0.88 STING1 (0.56) STING1ACHE
SCHEMBL29976207 0.88 STING1 (0.56) STING1ACHE
SCHEMBL25692519 0.83 STING1 (0.54) STING1ACHE
SCHEMBL20022184 0.82 STING1 (1.00) STING1ACHE
SCHEMBL9203238 0.80 STING1 (0.68) STING1ACHE
SCHEMBL29975798 0.80 STING1 (0.59) STING1ACHE
SCHEMBL25692520 0.80 STING1 (0.59) STING1ACHE
SCHEMBL21405817 0.79 STING1 (0.83) STING1ACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024032782-A1 VACCINE ADJUVANTS AND USES THEREOF JACOBIO PHARMACEUTICALS CO.LTD. (CN) 2024-02-15 — — WO disclosed
EP-4313962-A1 NOVEL COMPOUNDS USEFUL AS STING AGONISTS AND USES THEREOF Jacobio Pharmaceuticals Co., Ltd. (CN) 2024-02-07 — — EP disclosed
WO-2023109942-A1 COMPOUND-LINKER CONSTRUCTS COMPRISING NOVEL COMPOUNDS USEFUL AS STING AGONISTS AND USES THEREOF JACOBIO PHARMACEUTICALS CO., LTD. (CN) 2023-06-22 — — WO disclosed
WO-2022206725-A1 NOVEL COMPOUNDS USEFUL AS STING AGONISTS AND USES THEREOF JACOBIO PHARMACEUTICALS CO., LTD. (CN) 2022-10-06 — — WO disclosed
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