Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STING1 | Q86WV6 | 16/20 | 0.56 |
| ▸ | ACHE | P22303 | 3/20 | 0.43 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25693665 | 1.00 | STING1 (0.56) | STING1ACHEPTPN2 | |
| SCHEMBL25692521 | 0.88 | STING1 (0.69) | STING1ACHE | |
| SCHEMBL29975893 | 0.88 | STING1 (0.69) | STING1ACHE | |
| SCHEMBL31463290 | 0.84 | PTPN2 (0.53) | STING1PTPN2 | |
| SCHEMBL20562477 | 0.84 | PTPN2 (0.53) | STING1PTPN2 | |
| SCHEMBL20022296 | 0.81 | STING1 (0.81) | STING1ACHE | |
| SCHEMBL21452623 | 0.81 | STING1 (0.61) | STING1ACHE | |
| SCHEMBL20562443 | 0.80 | STING1 (0.53) | STING1PTPN2 | |
| SCHEMBL29975646 | 0.80 | STING1 (0.53) | STING1PTPN2 | |
| SCHEMBL21406406 | 0.80 | STING1 (0.82) | STING1ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024032782-A1 | VACCINE ADJUVANTS AND USES THEREOF | JACOBIO PHARMACEUTICALS CO.LTD. (CN) | 2024-02-15 | — | — | WO | disclosed |
| EP-4313962-A1 | NOVEL COMPOUNDS USEFUL AS STING AGONISTS AND USES THEREOF | Jacobio Pharmaceuticals Co., Ltd. (CN) | 2024-02-07 | — | — | EP | disclosed |
| CN-117203194-A | Novel compounds useful as STING agonists and uses thereof | 北京加科思新药研发有限公司 | 2023-12-08 | — | — | CN | disclosed |
| WO-2023109942-A1 | COMPOUND-LINKER CONSTRUCTS COMPRISING NOVEL COMPOUNDS USEFUL AS STING AGONISTS AND USES THEREOF | JACOBIO PHARMACEUTICALS CO., LTD. (CN) | 2023-06-22 | — | — | WO | disclosed |
| WO-2022206725-A1 | NOVEL COMPOUNDS USEFUL AS STING AGONISTS AND USES THEREOF | JACOBIO PHARMACEUTICALS CO., LTD. (CN) | 2022-10-06 | — | — | WO | disclosed |