SCHEMBL29975935

SCHEMBL29975935

N[C@H](CNc1nc(-c2ccncc2)nc2sc3c(c12)CCCC3)Cc1ccccc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ PRKCI P41743 19/20 1.00
▸ PRKCZ Q05513 1/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14986580 1.00 PRKCI (1.00) PRKCIPRKCZ
SCHEMBL14986349 1.00 PRKCI (1.00) PRKCIPRKCZ
SCHEMBL16203432 0.99 PRKCI (1.00) PRKCIPRKCZ
SCHEMBL14986377 0.99 PRKCI (1.00) PRKCIPRKCZ
SCHEMBL14986594 0.99 PRKCI (1.00) PRKCIPRKCZ
SCHEMBL14986573 0.95 PRKCI (1.00) PRKCIPRKCZ
SCHEMBL14986469 0.93 PRKCI (1.00) PRKCIPRKCZ
SCHEMBL14986599 0.92 PRKCI (1.00) PRKCIPRKCZ
SCHEMBL14986466 0.92 PRKCI (1.00) PRKCIPRKCZ
SCHEMBL20875230 0.92 PRKCI (1.00) PRKCIPRKCZ

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250312332-A1 TREATMENT OF MUSCLE FIBROSIS FUNDACIÓ INSTITUT DE RECERCA DE L'HOSPITAL DE LA SANTA CREU I SANT PAU (ES) 2025-10-09 — — US claimed
WO-2023223519-A1 METHOD FOR DEACTIVATING ACTIVATED STELLATE CELLS ISM株式会社 2023-11-23 — — WO claimed
WO-2023199010-A1 TREATMENT OF MUSCLE FIBROSIS UNIVERSITY OF NEWCASTLE UPON TYNE (GB) 2023-10-19 — — WO claimed
US-20250312332-A1 TREATMENT OF MUSCLE FIBROSIS FUNDACIÓ INSTITUT DE RECERCA DE L'HOSPITAL DE LA SANTA CREU I SANT PAU (ES) 2025-10-09 — — US disclosed
US-20250304916-A1 METHODS AND COMPOSITIONS FOR GENERATING VASCULAR LEPTOMENINGEAL CELLS TRAILHEAD BIOSYSTEMS INC (US) 2025-10-02 — — US disclosed
WO-2025094914-A1 TRANSPLANTATION DEVICE CAPABLE OF ENCAPSULATING CELLS THEREIN AND USE THEREOF 株式会社VC Cell Therapy 2025-05-08 — — WO disclosed
US-20240400983-A1 CELL AGGREGATE INCLUDING PITUITARY HORMONE-PRODUCING CELLS AND METHOD FOR PRODUCING SAME Sumitomo Pharma Co., Ltd. (JP) 2024-12-05 — — US disclosed
US-20240392241-A1 METHOD FOR PRODUCING CELL MASS INCLUDING PITUITARY TISSUE AND CELL MASS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2024-11-28 — — US disclosed
WO-2024171957-A1 TRANSPLANTATION OF PITUITARY HORMONE-PRODUCING CELLS 国立大学法人東海国立大学機構 2024-08-22 — — WO disclosed
EP-4410962-A1 CELL AGGREGATE INCLUDING PITUITARY HORMONE-PRODUCING CELLS AND METHOD FOR PRODUCING SAME Sumitomo Pharma Co., Ltd. (JP) 2024-08-07 — — EP disclosed
EP-4410963-A1 METHOD FOR PRODUCING CELL MASS INCLUDING PITUITARY TISSUE AND CELL MASS Sumitomo Chemical Company, Limited (JP) 2024-08-07 — — EP disclosed
CN-116987667-A Method for differentiating pluripotent stem cells into macrophages or neutrophils 天海元祺生物科技(天津)有限公司 2023-11-03 — — CN disclosed
WO-2023199010-A1 TREATMENT OF MUSCLE FIBROSIS UNIVERSITY OF NEWCASTLE UPON TYNE (GB) 2023-10-19 — — WO disclosed
CN-116731967-A Method for preparing macrophage from multipotent stem cells by induced differentiation 南京大学 2023-09-12 — — CN disclosed
US-20230149295-A1 INFLAMMATORY BOWEL DISEASE STEM CELLS, AGENTS WHICH TARGET IBD STEM CELLS, AND USES RELATED THERETO UNIVERSITY OF HOUSTON SYSTEM (US) 2023-05-18 — — US disclosed
WO-2023054395-A1 CELL AGGREGATE INCLUDING PITUITARY HORMONE-PRODUCING CELLS AND METHOD FOR PRODUCING SAME 住友ファーマ株式会社 2023-04-06 — — WO disclosed
WO-2023054396-A1 METHOD FOR PRODUCING CELL MASS INCLUDING PITUITARY TISSUE AND CELL MASS 住友化学株式会社 2023-04-06 — — WO disclosed
EP-4117718-A1 INFLAMMATORY BOWEL DISEASE STEM CELLS, AGENTS WHICH TARGET IBD STEM CELLS, AND USES RELATED THERETO University of Houston System (US) 2023-01-18 — — EP disclosed
WO-2023277135-A1 METHOD FOR PRODUCING CELLS CONSTITUTING NASAL EPITHELIUM, AND CELL POPULATION INCLUDING CELLS CONSTITUTING NASAL EPITHELIUM OR PROGENITOR CELLS THEREOF 住友化学株式会社 2023-01-05 — — WO disclosed
WO-2022230977-A1 CORD-LIKE AGGREGATES OF RETINAL PIGMENT EPITHELIAL CELLS, DEVICE AND PRODUCTION METHOD FOR PRODUCING SAME, AND THERAPEUTIC AGENT COMPRISING SAID CORD-LIKE AGGREGATES 国立研究開発法人理化学研究所 2022-11-03 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250312332-A1 TREATMENT OF MUSCLE FIBROSIS RHOA, MYLK2, MYLK PRKCI 355/4885PRKCZ 369/4885
US-20230149295-A1 INFLAMMATORY BOWEL DISEASE STEM CELLS, AGENTS WHICH TARGET IBD STEM CELLS, AND USES RELATED THERETO EPCAM, FABP2, TPMT PRKCI 1553/4885PRKCZ 2187/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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