Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 1/20 | 0.45 |
| ▸ | MET | P08581 | 2/20 | 0.44 |
| ▸ | SDHB | P21912 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 11/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | HPGD | P15428 | 6/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19805747 | 1.00 | ADORA2A (0.45) | ADORA2AMETSDHBKDM4EALDH1A1 | |
| SCHEMBL29976249 | 0.82 | SDHB (0.54) | ADORA2ASDHBKDM4EALDH1A1HPGD | |
| SCHEMBL19805905 | 0.82 | SDHB (0.54) | ADORA2ASDHBKDM4EALDH1A1HPGD | |
| SCHEMBL29976621 | 0.81 | SDHB (0.59) | ADORA2ASDHBKDM4EALDH1A1HPGD | |
| SCHEMBL19805635 | 0.81 | SDHB (0.59) | ADORA2ASDHBKDM4EALDH1A1HPGD | |
| SCHEMBL19805742 | 0.81 | ADORA2A (0.53) | ADORA2ASDHBKDM4EALDH1A1HPGD | |
| SCHEMBL29977092 | 0.81 | ADORA2A (0.53) | ADORA2ASDHBKDM4EALDH1A1HPGD | |
| SCHEMBL19805751 | 0.80 | KDM4E (0.51) | ADORA2AMETSDHBKDM4EALDH1A1 | |
| SCHEMBL29976339 | 0.79 | TP53 (0.49) | ADORA2ASDHBKDM4EALDH1A1HPGD | |
| SCHEMBL19805732 | 0.79 | TP53 (0.49) | ADORA2ASDHBKDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110023292-B | Apoptosis inhibitors | 北京生命科学研究所 | 2022-10-04 | — | — | CN | disclosed |