Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SDHB | P21912 | 15/20 | 0.86 |
| ▸ | TP53 | P04637 | 4/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | STAT3 | P40763 | 2/20 | 0.54 |
| ▸ | STAT1 | P42224 | 2/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20985646 | 1.00 | SDHB (0.86) | SDHBTP53SMN1; SMN2POLBSTAT3 | |
| SCHEMBL29976258 | 0.92 | SDHB (1.00) | SDHBTP53SMN1; SMN2POLBSTAT3 | |
| SCHEMBL20985736 | 0.92 | SDHB (1.00) | SDHBTP53SMN1; SMN2POLBSTAT3 | |
| SCHEMBL20985632 | 0.91 | SDHB (0.86) | SDHBTP53SMN1; SMN2 | |
| SCHEMBL29975634 | 0.91 | SDHB (0.86) | SDHBTP53SMN1; SMN2 | |
| SCHEMBL19806004 | 0.91 | SDHB (0.95) | SDHB | |
| SCHEMBL20985622 | 0.90 | SDHB (1.00) | SDHBTP53SMN1; SMN2POLBSTAT3 | |
| SCHEMBL30526080 | 0.90 | SDHB (1.00) | SDHBTP53SMN1; SMN2POLBSTAT3 | |
| SCHEMBL20985648 | 0.90 | SDHB (1.00) | SDHB | |
| SCHEMBL20985671 | 0.90 | SDHB (1.00) | SDHB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110023292-B | Apoptosis inhibitors | 北京生命科学研究所 | 2022-10-04 | — | — | CN | disclosed |