Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.40 |
| ▸ | TUBB | P07437 | 1/20 | 0.40 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.40 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.40 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.40 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.40 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.40 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.40 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.40 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.40 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.40 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.40 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.40 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.40 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22025650 | 1.00 | MAPT (0.46) | MAPTMAPK1TDP1ALDH1A1LMNA | |
| SCHEMBL23153813 | 0.82 | MAPT (0.43) | MAPTMAPK1TDP1ALDH1A1LMNA | |
| SCHEMBL29661436 | 0.80 | ALDH1A1 (0.50) | MAPTTDP1ALDH1A1LMNATUBB4A | |
| SCHEMBL517768 | 0.80 | ALDH1A1 (0.50) | MAPTTDP1ALDH1A1LMNATUBB4A | |
| SCHEMBL31757016 | 0.79 | ALDH1A1 (0.51) | MAPTTDP1ALDH1A1LMNATUBB4A | |
| SCHEMBL30801468 | 0.79 | ALDH1A1 (0.48) | MAPTTDP1ALDH1A1LMNATUBB4A | |
| SCHEMBL12458650 | 0.79 | ALDH1A1 (0.48) | MAPTTDP1ALDH1A1LMNATUBB4A | |
| SCHEMBL4647775 | 0.77 | ATM (0.44) | MAPTMAPK1TDP1ALDH1A1LMNA | |
| SCHEMBL29508908 | 0.76 | ALDH1A1 (0.46) | MAPTMAPK1TDP1ALDH1A1LMNA | |
| SCHEMBL310694 | 0.76 | ALDH1A1 (0.46) | MAPTMAPK1TDP1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025067509-A1 | EGFR DEGRADANT, AND PREPARATION METHOD AND USE THEREFOR | 石药集团中奇制药技术（石家庄）有限公司 | 2025-04-03 | — | — | WO | disclosed |
| WO-2022228547-A1 | PHOSPHONYL DERIVATIVE, AND COMPOSITION AND PHARMACEUTICAL APPLICATION THEREOF | 四川海思科制药有限公司 | 2022-11-03 | — | — | WO | disclosed |