SCHEMBL29976289

SCHEMBL29976289

CCCCC(c1cc(C(C)(C)C)cc(C(C)(C)C)c1O)c1cc(C(C)(C)C)cc(C(C)(C)C)c1O

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2C19 P33261 4/20 0.62
CYP2C9 P11712 3/20 0.62
CYP3A4 P08684 2/20 0.62
TSHR P16473 2/20 0.62
CYP1A2 P05177 1/20 0.62
NR5A2 O00482 1/20 0.48
NR5A1 Q13285 1/20 0.48
TP53 P04637 1/20 0.44
CYP2D6 P10635 1/20 0.44
ALOX15 P16050 1/20 0.44
HSP90AA1 P07900 1/20 0.40
GAA P10253 3/20 0.36
ALDH1A1 P00352 3/20 0.36
XBP1 P17861 2/20 0.36
NPSR1 Q6W5P4 2/20 0.36
ATM Q13315 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
MAPK1 P28482 1/20 0.36
HTT P42858 1/20 0.36
CA2 P00918 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11327432 1.00 CYP2C19 (0.62) CYP2C19CYP2C9CYP3A4TSHRCYP1A2
SCHEMBL10663388 0.94 CYP2C9 (0.59) CYP2C19CYP2C9CYP3A4TSHRCYP1A2
SCHEMBL4594355 0.90 CYP2C19 (0.66) CYP2C19CYP2C9CYP3A4TSHRCYP1A2
SCHEMBL9068045 0.84 SMN1; SMN2 (0.52) CYP2C19CYP2C9CYP3A4TSHRCYP1A2
SCHEMBL2164224 0.83 CYP2C19 (0.79) CYP2C19CYP2C9CYP3A4TSHRCYP1A2
SCHEMBL27075791 0.83 HSPA5 (0.51) CYP2C19CYP2C9CYP3A4TSHRCYP1A2
SCHEMBL6400593 0.82 CYP2C9 (0.43) CYP2C19CYP2C9CYP3A4TSHRCYP1A2
SCHEMBL8851966 0.82 CYP2C19 (0.67) CYP2C19CYP2C9CYP3A4TSHRCYP1A2
SCHEMBL11236535 0.81 CYP2C9 (0.49) CYP2C19CYP2C9CYP3A4TSHRCYP1A2
Acrylic Acid SCHEMBL9576773 0.80 CYP2C9 (0.54) CYP2C19CYP2C9CYP3A4TSHRCYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022210295-A1 PHOSPHOROUS ESTER COMPOUND, METHOD FOR PRODUCING SAME, AND USE APPLICATION FOR SAME 住友化学株式会社 2022-10-06 WO disclosed