SCHEMBL8851966

SCHEMBL8851966

CC(C)(C)c1cc(C(CC(c2cc(C(C)(C)C)cc(C(C)(C)C)c2O)c2cc(C(C)(C)C)cc(C(C)(C)C)c2O)c2cc(C(C)(C)C)cc(C(C)(C)C)c2O)c(O)c(C(C)(C)C)c1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2C19 P33261 6/20 0.67
CYP2C9 P11712 5/20 0.67
CYP3A4 P08684 3/20 0.67
TSHR P16473 3/20 0.67
CYP1A2 P05177 3/20 0.67
CA2 P00918 3/20 0.42
CA1 P00915 2/20 0.42
HSP90AA1 P07900 1/20 0.41
ALDH1A1 P00352 4/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
POLB P06746 1/20 0.41
TYR P14679 1/20 0.41
NR5A2 O00482 1/20 0.40
NR5A1 Q13285 1/20 0.40
GLRA3 O75311 1/20 0.40
GLRB P48167 1/20 0.40
GABRA1 P14867 1/20 0.39
GABRB2 P47870 1/20 0.39
GAA P10253 2/20 0.38
LMNA P02545 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6397556 0.91 CYP2C19 (0.61) CYP2C19CYP2C9CYP3A4TSHRCYP1A2
SCHEMBL2164224 0.87 CYP2C19 (0.79) CYP2C19CYP2C9CYP3A4TSHRCYP1A2
SCHEMBL8990182 0.87 CYP2C19 (0.57) CYP2C19CYP2C9CYP3A4TSHRCYP1A2
SCHEMBL4594355 0.84 CYP2C19 (0.66) CYP2C19CYP2C9CYP3A4TSHRCYP1A2
SCHEMBL27964696 0.82 CYP2C19 (0.58) CYP2C19CYP2C9CYP3A4TSHRCYP1A2
SCHEMBL817163 0.82 CYP2C19 (0.58) CYP2C19CYP2C9CYP3A4TSHRCYP1A2
SCHEMBL29976289 0.82 CYP2C19 (0.62) CYP2C19CYP2C9CYP3A4TSHRCYP1A2
SCHEMBL5025933 0.82 CYP2C19 (0.58) CYP2C19CYP2C9CYP3A4TSHRCYP1A2
SCHEMBL11327432 0.82 CYP2C19 (0.62) CYP2C19CYP2C9CYP3A4TSHRCYP1A2
SCHEMBL6768184 0.81 CYP1A2 (0.57) CYP2C19CYP2C9CYP3A4TSHRCYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102455597-B X-ray sensitive resin composition, cured film and forming method thereof, liquid crystal display cells array base palte and forming method thereof JSR株式会社 2016-06-29 CN disclosed
CN-102892849-B curable powder coating composition and cured product thereof NIPPON SODA CO.,LTD. (JP) 2016-01-20 CN disclosed
CN-102298264-B Radiation-sensitive resin composition for forming cured film, method of manufacturing the same, cured film, method for forming the cured film and display device JSR CORP 2015-02-18 CN disclosed
CN-102574988-B Composition for formation of cured epoxy resin, and cured products thereof NIPPON SODA CO 2014-05-14 CN disclosed
US-5604176-A BASIC DYE, DEVELOPER, POLYETHYLENE ON SUPPORT NEW OJI PAPER CO., LTD. (JP) 1997-02-18 US disclosed
EP-0376886-B1 PIPERIDINE-TRIAZINE COMPOUNDS FOR USE AS STABILIZERS FOR ORGANIC MATERIALS CIBA-GEIGY AG (CH) 1993-07-28 EP disclosed
US-5216052-A Useful for stabilization of synthetic polymers against oxidative, thermal and light-induced degradation CIBA-GEIGY CORPORATION (US) 1993-06-01 US disclosed
EP-0376886-A1 Piperidine-triazine compounds for use as stabilizers for organic materials CIBA-GEIGY AG (CH) 1990-07-04 EP disclosed