Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK9 | P50750 | 1/20 | 0.47 |
| ▸ | CRBN | Q96SW2 | 13/20 | 0.47 |
| ▸ | IRAK1 | P51617 | 2/20 | 0.46 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.46 |
| ▸ | IRAK3 | Q9Y616 | 2/20 | 0.46 |
| ▸ | AR | P10275 | 6/20 | 0.46 |
| ▸ | DDB1 | Q16531 | 2/20 | 0.44 |
| ▸ | BTK | Q06187 | 1/20 | 0.44 |
| ▸ | PLK4 | O00444 | 2/20 | 0.43 |
| ▸ | ALK | Q9UM73 | 2/20 | 0.42 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.41 |
| ▸ | CCNC | P24863 | 1/20 | 0.41 |
| ▸ | CDK8 | P49336 | 1/20 | 0.41 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.41 |
| ▸ | HASPIN | Q8TF76 | 1/20 | 0.41 |
| ▸ | CDK19 | Q9BWU1 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | ITK | Q08881 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27162159 | 1.00 | CDK9 (0.47) | CDK9CRBNIRAK1IRAK4IRAK3 | |
| SCHEMBL29976842 | 0.98 | CDK9 (0.49) | CDK9CRBNIRAK1IRAK4IRAK3 | |
| SCHEMBL27161964 | 0.98 | CDK9 (0.49) | CDK9CRBNIRAK1IRAK4IRAK3 | |
| SCHEMBL29976262 | 0.98 | CRBN (0.47) | CDK9CRBNIRAK1IRAK4IRAK3 | |
| SCHEMBL27161991 | 0.98 | CRBN (0.47) | CDK9CRBNIRAK1IRAK4IRAK3 | |
| SCHEMBL29976265 | 0.96 | CRBN (0.44) | CDK9CRBNIRAK1IRAK4IRAK3 | |
| SCHEMBL27163130 | 0.96 | CRBN (0.44) | CDK9CRBNIRAK1IRAK4IRAK3 | |
| SCHEMBL28795245 | 0.93 | CRBN (0.47) | CDK9CRBNIRAK1IRAK4IRAK3 | |
| SCHEMBL29976075 | 0.93 | CRBN (0.49) | CDK9CRBNIRAK1IRAK4IRAK3 | |
| SCHEMBL27161955 | 0.93 | CRBN (0.49) | CDK9CRBNIRAK1IRAK4IRAK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022228547-A1 | PHOSPHONYL DERIVATIVE, AND COMPOSITION AND PHARMACEUTICAL APPLICATION THEREOF | 四川海思科制药有限公司 | 2022-11-03 | — | — | WO | disclosed |