Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.50 |
| ▸ | RAB9A | P51151 | 4/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | DHODH | Q02127 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | MAPK13 | O15264 | 2/20 | 0.35 |
| ▸ | MAPK12 | P53778 | 2/20 | 0.35 |
| ▸ | MAPK11 | Q15759 | 2/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.35 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.35 |
| ▸ | CDK2 | P24941 | 1/20 | 0.35 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29976542 | 0.92 | SMN1; SMN2 (0.41) | SMN1; SMN2RAB9ANPC1KDM4EALDH1A1 | |
| SCHEMBL29977188 | 0.92 | SMN1; SMN2 (0.40) | SMN1; SMN2RAB9ANPC1KDM4EALDH1A1 | |
| SCHEMBL29977036 | 0.86 | SMN1; SMN2 (0.36) | SMN1; SMN2RAB9ANPC1KDM4EALDH1A1 | |
| SCHEMBL29977354 | 0.85 | CSNK2A2 (0.35) | SMN1; SMN2RAB9ANPC1KMT2A | |
| SCHEMBL29976800 | 0.85 | SMN1; SMN2 (0.36) | SMN1; SMN2RAB9ANPC1KDM4EALDH1A1 | |
| SCHEMBL29977250 | 0.84 | IRAK4 (0.35) | SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL29976735 | 0.83 | SCD (0.37) | SMN1; SMN2KDM4EALDH1A1HPGDKMT2A | |
| SCHEMBL29976557 | 0.83 | PSEN1 (0.33) | SMN1; SMN2RAB9ANPC1CCNE1CDK2 | |
| SCHEMBL29977028 | 0.82 | KDR (0.38) | — | |
| SCHEMBL29977049 | 0.81 | GAA (0.32) | SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115403558-A | Aromatic heterocyclic compound with antitumor activity and preparation method and application thereof | 河南真实生物科技有限公司 | 2022-11-29 | — | — | CN | disclosed |