Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSEN1 | P49768 | 1/20 | 0.33 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.33 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.33 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.33 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.33 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | PKLR | P30613 | 1/20 | 0.32 |
| ▸ | ALPL | P05186 | 1/20 | 0.32 |
| ▸ | ALPI | P09923 | 1/20 | 0.32 |
| ▸ | CDK2 | P24941 | 2/20 | 0.31 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.31 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 2/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29977354 | 0.84 | CSNK2A2 (0.35) | PKMPKLRRAB9ASMN1; SMN2NPC1 | |
| SCHEMBL29977188 | 0.83 | SMN1; SMN2 (0.40) | RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL29976559 | 0.83 | SMN1; SMN2 (0.50) | CDK2CCNE1CDK5RAB9ASMN1; SMN2 | |
| SCHEMBL29976542 | 0.83 | SMN1; SMN2 (0.41) | RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL29977250 | 0.83 | IRAK4 (0.35) | PKMPKLRALPLALPIRAB9A | |
| SCHEMBL29977028 | 0.81 | KDR (0.38) | — | |
| SCHEMBL29976735 | 0.80 | SCD (0.37) | ALPLALPISMN1; SMN2 | |
| SCHEMBL29976548 | 0.78 | PLA2G7 (0.41) | PKMRAB9ASMN1; SMN2NPC1 | |
| SCHEMBL29977049 | 0.78 | GAA (0.32) | SMN1; SMN2 | |
| SCHEMBL29976739 | 0.78 | ALPL (0.35) | ALPLALPI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115403558-A | Aromatic heterocyclic compound with antitumor activity and preparation method and application thereof | 河南真实生物科技有限公司 | 2022-11-29 | — | — | CN | disclosed |