Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.57 |
| ▸ | HPGD | P15428 | 8/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.57 |
| ▸ | TP53 | P04637 | 3/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.57 |
| ▸ | USP2 | O75604 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 9/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | GLA | P06280 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19805666 | 1.00 | KDM4E (0.63) | KDM4EALDH1A1HPGDSMN1; SMN2KMT2A | |
| SCHEMBL19805642 | 0.81 | SDHB (0.48) | KDM4EALDH1A1HPGDSMN1; SMN2KMT2A | |
| SCHEMBL29976174 | 0.81 | SDHB (0.48) | KDM4EALDH1A1HPGDSMN1; SMN2KMT2A | |
| SCHEMBL29976309 | 0.81 | SDHB (0.69) | TP53MAPT | |
| SCHEMBL19805871 | 0.81 | SDHB (0.69) | TP53MAPT | |
| SCHEMBL19805669 | 0.81 | SDHB (0.52) | KDM4EALDH1A1HPGDSMN1; SMN2KMT2A | |
| SCHEMBL19805680 | 0.79 | MEN1 (0.49) | HPGDKMT2AMEN1LMNA | |
| SCHEMBL28348177 | 0.77 | KDM4E (0.69) | KDM4EALDH1A1HPGDSMN1; SMN2KMT2A | |
| SCHEMBL30230259 | 0.77 | KDM4E (0.69) | KDM4EALDH1A1HPGDSMN1; SMN2KMT2A | |
| SCHEMBL19805624 | 0.76 | SDHB (0.61) | KDM4EALDH1A1HPGDSMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110023292-B | Apoptosis inhibitors | 北京生命科学研究所 | 2022-10-04 | — | — | CN | disclosed |