Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.63 |
| ▸ | POLB | P06746 | 2/20 | 0.63 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | HPGD | P15428 | 5/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.43 |
| ▸ | SDHB | P21912 | 2/20 | 0.42 |
| ▸ | ADRB2 | P07550 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19806062 | 0.84 | SDHB (0.59) | LMNAPOLBMAPK1MEN1KMT2A | |
| SCHEMBL29977085 | 0.84 | MEN1 (0.44) | LMNAPOLBMAPK1MEN1KMT2A | |
| SCHEMBL19805929 | 0.84 | MEN1 (0.44) | LMNAPOLBMAPK1MEN1KMT2A | |
| SCHEMBL19805783 | 0.82 | MEN1 (0.42) | LMNAPOLBMAPK1MEN1KMT2A | |
| SCHEMBL20985676 | 0.81 | MEN1 (0.51) | LMNAPOLBMAPK1MEN1KMT2A | |
| SCHEMBL19805738 | 0.78 | SDHB (0.67) | LMNAPOLBMAPK1TSHRMEN1 | |
| SCHEMBL20985728 | 0.78 | SDHB (0.49) | LMNAPOLBMAPK1TSHRMEN1 | |
| SCHEMBL19806057 | 0.76 | MEN1 (0.51) | LMNAPOLBMAPK1MEN1KMT2A | |
| SCHEMBL29976351 | 0.76 | MEN1 (0.51) | LMNAPOLBMAPK1MEN1KMT2A | |
| SCHEMBL20985721 | 0.76 | MEN1 (0.40) | LMNAPOLBMAPK1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110023292-B | Apoptosis inhibitors | 北京生命科学研究所 | 2022-10-04 | — | — | CN | disclosed |