SCHEMBL29977339

SCHEMBL29977339

COc1cncc(B2OC(C)(C)C(C)(C)O2)c1C

nearest known ligand 0.35

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
UCHL1 P09936 1/20 0.35
EGFR P00533 2/20 0.33
CSF1R P07333 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24667027 1.00 UCHL1 (0.35) UCHL1EGFRCSF1R
SCHEMBL29175545 0.79 UCHL1 (0.34) UCHL1
SCHEMBL31200876 0.79 CSF1R (0.32) UCHL1EGFRCSF1R
SCHEMBL26985737 0.77 PTGS1 (0.40) UCHL1
SCHEMBL26985713 0.77 NCEH1 (0.37) UCHL1
SCHEMBL30746484 0.77 PTGS1 (0.40) UCHL1
SCHEMBL30746702 0.77 NCEH1 (0.37) UCHL1
SCHEMBL3140900 0.77 CA12 (0.36) UCHL1EGFRCSF1R
SCHEMBL12435832 0.77 CA12 (0.39) UCHL1EGFRCSF1R
SCHEMBL30494157 0.77 CA12 (0.39) UCHL1EGFRCSF1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4622967-A1 COMPOUNDS THAT INHIBIT PKMYT1 Exelixis, Inc. (US) 2025-10-01 EP disclosed
WO-2024112853-A1 COMPOUNDS THAT INHIBIT PKMYT1 EXELIXIS, INC. (US) 2024-05-30 WO disclosed
WO-2022236319-A1 NAPHTHYRIDONE COMPOUNDS FOR INHIBITION OF RAF KINASES AND/OR BCR-ABL TYROSINE KINASES ENLIVEN THERAPEUTICS, INC. (US) 2022-11-10 WO disclosed