Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 11/20 | 0.54 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | HRH2 | P25021 | 1/20 | 0.54 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.54 |
| ▸ | HTR2A | P28223 | 1/20 | 0.54 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.54 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.54 |
| ▸ | HTR2B | P41595 | 1/20 | 0.54 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.54 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.54 |
| ▸ | TLR8 | Q9NR97 | 6/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29977556 | 0.87 | LMNA (0.38) | TLR7ADORA2ALMNAPOLBHRH2 | |
| SCHEMBL29977597 | 0.85 | TLR7 (0.57) | TLR7ADORA2ALMNAPOLBHRH2 | |
| SCHEMBL29809478 | 0.85 | TLR7 (0.57) | TLR7ADORA2ALMNAPOLBHRH2 | |
| SCHEMBL24732765 | 0.85 | TLR7 (0.57) | TLR7ADORA2ALMNAPOLBHRH2 | |
| SCHEMBL29808887 | 0.83 | TLR7 (0.54) | TLR7ADORA2ALMNAPOLBHRH2 | |
| SCHEMBL24732579 | 0.83 | TLR7 (0.54) | TLR7ADORA2ALMNAPOLBHRH2 | |
| SCHEMBL27213598 | 0.78 | TLR7 (0.47) | TLR7TLR8 | |
| SCHEMBL29977942 | 0.78 | TLR7 (0.48) | TLR7ADORA2ALMNAPOLBHRH2 | |
| SCHEMBL3188618 | 0.77 | TLR7 (0.67) | TLR7ADORA2ALMNAPOLBHRH2 | |
| Hydrochloric Acid SCHEMBL3197884 | 0.76 | TLR7 (0.66) | TLR7ADORA2ALMNAPOLBHRH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022161420-A1 | CLASS OF HETEROAROMATIC COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF | 上海翊石医药科技有限公司 | 2022-08-04 | — | — | WO | disclosed |