Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 10/20 | 0.50 |
| ▸ | CA12 | O43570 | 3/20 | 0.50 |
| ▸ | CA2 | P00918 | 3/20 | 0.50 |
| ▸ | CA9 | Q16790 | 3/20 | 0.50 |
| ▸ | CA1 | P00915 | 2/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | HAO1 | Q9UJM8 | 2/20 | 0.38 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25490046 | 1.00 | GRM5 (0.50) | GRM5CA12CA2CA9CA1 | |
| SCHEMBL9302636 | 0.85 | CA12 (0.62) | GRM5CA12CA2CA9CA1 | |
| SCHEMBL31286312 | 0.85 | CA12 (0.62) | GRM5CA12CA2CA9CA1 | |
| SCHEMBL718613 | 0.84 | CA12 (0.52) | GRM5CA12CA2CA9CA1 | |
| SCHEMBL30559799 | 0.83 | APP (0.38) | GRM5CA12CA2CA9CA1 | |
| SCHEMBL717450 | 0.79 | CA12 (0.59) | GRM5CA12CA2CA9CA1 | |
| SCHEMBL848355 | 0.77 | CA12 (0.50) | GRM5CA12CA2CA9CA1 | |
| SCHEMBL935880 | 0.77 | CA12 (0.50) | GRM5CA12CA2CA9CA1 | |
| SCHEMBL9304700 | 0.77 | CA12 (0.62) | GRM5CA12CA2CA9CA1 | |
| SCHEMBL15540865 | 0.77 | CA12 (0.50) | GRM5CA12CA2CA9CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118063444-A | Azetidinamide derivatives and uses thereof | 广东东阳光药业股份有限公司 | 2024-05-24 | — | — | CN | disclosed |
| CN-111072604-B | Alpha-aminoamide derivatives and use thereof | 广东东阳光药业有限公司 | 2022-11-04 | — | — | CN | disclosed |