Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A2 | O15244 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | XBP1 | P17861 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.34 |
| ▸ | RELA | Q04206 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | NTRK1 | P04629 | 7/20 | 0.34 |
| ▸ | JAK2 | O60674 | 6/20 | 0.34 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.34 |
| ▸ | FLT4 | P35916 | 1/20 | 0.34 |
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
| ▸ | RARB | P10826 | 1/20 | 0.34 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18313281 | 1.00 | SLC22A2 (0.35) | SLC22A2KDM4EALDH1A1LMNAPOLB | |
| SCHEMBL19986992 | 0.91 | KMT2A (0.36) | SLC22A2NTRK1JAK2KMT2ACNR1 | |
| SCHEMBL29457322 | 0.91 | KMT2A (0.36) | SLC22A2NTRK1JAK2KMT2ACNR1 | |
| SCHEMBL19986990 | 0.91 | KMT2A (0.36) | SLC22A2NTRK1JAK2KMT2ACNR1 | |
| SCHEMBL18313580 | 0.90 | KDM4E (0.34) | KDM4EALDH1A1LMNAPOLBHPGD | |
| SCHEMBL18312369 | 0.89 | KDM4E (0.36) | SLC22A2KDM4EALDH1A1LMNAPOLB | |
| SCHEMBL18313265 | 0.89 | KDM4E (0.36) | SLC22A2KDM4EALDH1A1LMNAPOLB | |
| SCHEMBL20531767 | 0.89 | KDM4E (0.36) | SLC22A2KDM4EALDH1A1LMNAPOLB | |
| SCHEMBL18313142 | 0.89 | KDM4E (0.36) | SLC22A2KDM4EALDH1A1LMNAPOLB | |
| SCHEMBL19784204 | 0.89 | KDM4E (0.36) | SLC22A2KDM4EALDH1A1LMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109689656-B | 7-substituted 1-arylnaphthyridine-3-carboxamides and their use | 拜耳股份公司 | 2022-10-04 | — | — | CN | disclosed |