Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | PDE2A | O00408 | 1/20 | 0.35 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.35 |
| ▸ | PRKDC | P78527 | 1/20 | 0.35 |
| ▸ | NTRK1 | P04629 | 3/20 | 0.34 |
| ▸ | JAK2 | O60674 | 2/20 | 0.34 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.34 |
| ▸ | IRAK4 | Q9NWZ3 | 4/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.33 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.33 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.33 |
| ▸ | RAF1 | P04049 | 1/20 | 0.33 |
| ▸ | BRAF | P15056 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29457322 | 1.00 | KMT2A (0.36) | KMT2APDE2ASLC22A2PRKDCNTRK1 | |
| SCHEMBL19986990 | 1.00 | KMT2A (0.36) | KMT2APDE2ASLC22A2PRKDCNTRK1 | |
| SCHEMBL29979696 | 0.91 | SLC22A2 (0.35) | KMT2ASLC22A2NTRK1JAK2CNR1 | |
| SCHEMBL18313281 | 0.91 | SLC22A2 (0.35) | KMT2ASLC22A2NTRK1JAK2CNR1 | |
| SCHEMBL22591922 | 0.90 | ALDH1A1 (0.35) | KMT2APDE2APRKDCMAPK8IRAK4 | |
| SCHEMBL19784203 | 0.90 | KMT2A (0.37) | KMT2ANTRK1JAK2MAPK8IRAK4 | |
| SCHEMBL19971411 | 0.89 | KMT2A (0.46) | KMT2APDE2ASLC22A2NTRK1NTRK3 | |
| SCHEMBL19987000 | 0.89 | KMT2A (0.46) | KMT2APDE2ASLC22A2NTRK1NTRK3 | |
| SCHEMBL22331829 | 0.87 | KMT2A (0.36) | KMT2APDE2ASLC22A2PRKDCMAPK8 | |
| SCHEMBL19987088 | 0.87 | KMT2A (0.40) | KMT2APDE2ASLC22A2NTRK1IRAK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018050510-A1 | 7-SUBSTITUTED 1-ARYL-NAPHTHYRIDINE-3-CARBOXYLIC ACID AMIDES AND USE THEREOF | BAYER AKTIENGESELLSCHAFT (DE) | 2018-03-22 | — | — | WO | disclosed |