Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | TNF | P01375 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.43 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24681676 | 0.85 | ALDH1A1 (0.43) | GAAKDM4ESMN1; SMN2TDP1HPGD | |
| SCHEMBL21132657 | 0.85 | ALDH1A1 (0.43) | GAAKDM4ESMN1; SMN2TDP1HPGD | |
| SCHEMBL21132891 | 0.85 | ALDH1A1 (0.43) | GAAKDM4ESMN1; SMN2TDP1HPGD | |
| SCHEMBL29283156 | 0.81 | GAA (0.66) | GAAKDM4ESMN1; SMN2TDP1HPGD | |
| SCHEMBL28926370 | 0.81 | GAA (0.42) | GAAKDM4ESMN1; SMN2TDP1HPGD | |
| SCHEMBL2227563 | 0.79 | HPGD (0.46) | GAAKDM4ESMN1; SMN2TDP1HPGD | |
| SCHEMBL4322056 | 0.77 | KDM4E (0.47) | GAAKDM4ESMN1; SMN2HPGDRAB9A | |
| SCHEMBL8543691 | 0.77 | SSTR4 (0.42) | — | |
| SCHEMBL27351823 | 0.76 | HPGD (0.51) | GAATDP1HPGDRAB9AALDH1A1 | |
| SCHEMBL27853757 | 0.76 | ALDH1A1 (0.52) | GAAKDM4ESMN1; SMN2TDP1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4065575-A1 | SUBSTITUTED TRICYCLIC COMPOUNDS | Lupin Limited (IN) | 2022-10-05 | — | — | EP | disclosed |