Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | POLB | P06746 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA7 | P43166 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 5/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | GRM5 | P41594 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14626911 | 0.88 | ALDH1A1 (0.42) | ALDH1A1LMNAPOLBMEN1MAPT | |
| SCHEMBL3588954 | 0.84 | ALDH1A1 (0.59) | ALDH1A1LMNAPOLBMEN1MAPT | |
| SCHEMBL3314468 | 0.84 | ALDH1A1 (0.59) | ALDH1A1LMNAPOLBMEN1MAPT | |
| SCHEMBL23581936 | 0.81 | ALDH1A1 (0.53) | ALDH1A1LMNAPOLBMEN1MAPT | |
| SCHEMBL21138803 | 0.80 | ALDH1A1 (0.65) | ALDH1A1LMNAPOLBMEN1MAPT | |
| SCHEMBL27872556 | 0.79 | ALDH1A1 (0.63) | ALDH1A1LMNAPOLBMEN1MAPT | |
| SCHEMBL17150933 | 0.79 | ALDH1A1 (0.54) | ALDH1A1LMNAPOLBMEN1MAPT | |
| SCHEMBL14311858 | 0.78 | CA12 (0.48) | ALDH1A1MAPTKMT2ACA12CA1 | |
| SCHEMBL15808643 | 0.78 | CA12 (0.48) | ALDH1A1MAPTKMT2ACA12CA1 | |
| SCHEMBL15808574 | 0.78 | CA12 (0.48) | ALDH1A1MAPTKMT2ACA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11492350-B2 | Compounds and methods of use | TANGO THERAPEUTICS, INC. (US) | 2022-11-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11492350-B2 | Compounds and methods of use | F12, C1R, ABCG2 | ALDH1A1 128/4885LMNA 1976/4885POLB 3098/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.