Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.35 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24365852 | 0.88 | HDAC6 (0.30) | AAK1HDAC6 | |
| SCHEMBL24364969 | 0.88 | HDAC6 (0.30) | AAK1HDAC6 | |
| SCHEMBL30470143 | 0.88 | HDAC6 (0.30) | AAK1HDAC6 | |
| SCHEMBL24367587 | 0.88 | HDAC6 (0.30) | AAK1HDAC6 | |
| SCHEMBL30470399 | 0.88 | HDAC6 (0.30) | AAK1HDAC6 | |
| SCHEMBL29981506 | 0.86 | LOXL2 (0.46) | AAK1LOXL2 | |
| SCHEMBL24364976 | 0.84 | HDAC6 (0.41) | HDAC6 | |
| SCHEMBL32689015 | 0.84 | HDAC6 (0.41) | HDAC6 | |
| SCHEMBL29081633 | 0.84 | HDAC6 (0.41) | HDAC6 | |
| SCHEMBL24364879 | 0.84 | HDAC6 (0.34) | AAK1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11492350-B2 | Compounds and methods of use | TANGO THERAPEUTICS, INC. (US) | 2022-11-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11492350-B2 | Compounds and methods of use | F12, C1R, ABCG2 | AAK1 4778/4885LOXL2 3243/4885HDAC6 299/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.