SCHEMBL2998081

SCHEMBL2998081

NNC(=O)c1cc[nH]n1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL466479 0.81
SCHEMBL5161547 0.80 MEN1 (0.31)
SCHEMBL21176491 0.80 GABRR1 (0.35)
SCHEMBL5786716 0.80 ALDH1A1 (0.37)
SCHEMBL27814528 0.80 SCN9A (0.39)
SCHEMBL28308150 0.80 ALDH1A1 (0.35)
SCHEMBL7527727 0.79
SCHEMBL28128118 0.79
SCHEMBL27659077 0.79
SCHEMBL169064 0.79

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 118 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120025331-A Pyrazole hydrazide derivative containing phenylthiazole fragment and application thereof 安徽理工大学 2025-05-23 CN claimed
CN-119707816-A Pyrazole hydrazide derivative containing diphenyl ether unit as well as preparation method and application thereof 江苏海洋大学 2025-03-28 CN claimed
CN-116675677-B C8 urushiol derivative and preparation method and application thereof 中国林业科学研究院林产化学工业研究所 2023-09-26 CN claimed
CN-116675677-A C8 urushiol derivative and preparation method and application thereof 中国林业科学研究院林产化学工业研究所 2023-09-01 CN claimed
CN-105777639-A Pyrazole hydrazide compound and use thereof 浙江博仕达作物科技有限公司 2016-07-20 CN claimed
CN-103483313-A Novel hydrazide derivatives as well as preparation method and application thereof UNIV NANKAI 2014-01-01 CN claimed
EP-1773783-B1 METHOD FOR PREPARING N-PIPERIDINO-1,5-DIPHENYLPYRAZOLE-3-CARBOXAMIDE DERIVATIVES SANOFI AVENTIS (FR) 2010-05-05 EP claimed
CN-100537543-C Process for preparing N-piperidino-1, 5-diphenylpyrazole-3-carboxamide derivatives SANOFI AVENTIS (FR) 2009-09-09 CN claimed
US-7462632-B2 Method for the preparation of N-piperidino-1, 5-diphenylpyrazole-3-carboxamide derivatives SANOFI-AVENTIS (FR) 2008-12-09 US claimed
US-20080119653-A1 METHOD FOR THE PREPARATION OF N-PIPERIDINO-1, 5-DIPHENYLPYRAZOLE-3-CARBOXAMIDE DERIVATIVES SANOFI-AVENTIS (FR) 2008-05-22 US claimed
CN-1956963-A Process for preparing N-piperidino-1, 5-diphenylpyrazole-3-carboxamide derivatives SANOFI AVENTIS (FR) 2007-05-02 CN claimed
EP-1773783-A1 METHOD FOR PREPARING N-PIPERIDINO-1,5-DIPHENYLPYRAZOLE-3-CARBOXAMIDE DERIVATIVES Sanofi-Aventis (FR) 2007-04-18 EP claimed
US-20060258729-A1 Antibacterial pyrazole carboxylic acid hydrazides MICROBIOTIX, INC. 2006-11-16 US claimed
WO-2006021652-A1 METHOD FOR PREPARING N-PIPERIDINO-1,5-DIPHENYLPYRAZOLE-3-CARBOXAMIDE DERIVATIVES SANOFI-AVENTIS (FR) 2006-03-02 WO claimed
EP-1549143-A2 ANTIBACTERIAL PYRAZOLE CARBOXYLIC ACID HYDRAZIDES Microbiotix, Inc. (US) 2005-07-06 EP claimed
WO-2004094370-A2 ANTIBACTERIAL PYRAZOLE CARBOXYLIC ACID HYDRAZIDES MICROBIOTIX, INC. (US) 2004-11-04 WO claimed
US-4469692-A CENTRAL NERVOUS SYSTEM DEPRESSANTS ALKALOIDA VEGYESZETI GYAR (HU) 1984-09-04 US claimed
CN-119707816-B Pyrazole hydrazide derivative containing diphenyl ether unit as well as preparation method and application thereof 江苏海洋大学 2026-02-06 CN disclosed
EP-1464642-A1 NOVEL SUBSTITUTED PYRAZOLE DERIVATIVE, PROCESS FOR PRODUCING THE SAME, AND HERBICIDAL COMPOSITION CONTAINING THE SAME SDS Biotech K.K. (JP) 2004-10-06 EP disclosed
US-4469692-A CENTRAL NERVOUS SYSTEM DEPRESSANTS ALKALOIDA VEGYESZETI GYAR (HU) 1984-09-04 US disclosed