Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 5/20 | 0.43 |
| ▸ | ACACA | Q13085 | 3/20 | 0.43 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | CKS1B | P61024 | 1/20 | 0.36 |
| ▸ | SKP1 | P63208 | 1/20 | 0.36 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.36 |
| ▸ | XBP1 | P17861 | 1/20 | 0.36 |
| ▸ | LATS1 | O95835 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20718106 | 1.00 | ACACB (0.43) | ACACBACACAPTGDRTHRBALDH1A1 | |
| SCHEMBL20718104 | 1.00 | ACACB (0.43) | ACACBACACAPTGDRTHRBALDH1A1 | |
| SCHEMBL29980816 | 1.00 | ACACB (0.43) | ACACBACACAPTGDRTHRBALDH1A1 | |
| SCHEMBL20718103 | 1.00 | ACACB (0.43) | ACACBACACAPTGDRTHRBALDH1A1 | |
| SCHEMBL29982343 | 1.00 | ACACB (0.43) | ACACBACACAPTGDRTHRBALDH1A1 | |
| SCHEMBL29981576 | 1.00 | ACACB (0.43) | ACACBACACAPTGDRTHRBALDH1A1 | |
| SCHEMBL20718183 | 0.95 | ACACB (0.43) | ACACBACACAPTGDRTHRBALDH1A1 | |
| SCHEMBL20718182 | 0.95 | ACACB (0.43) | ACACBACACAPTGDRTHRBALDH1A1 | |
| SCHEMBL20718184 | 0.95 | ACACB (0.43) | ACACBACACAPTGDRTHRBALDH1A1 | |
| SCHEMBL29980863 | 0.95 | ACACB (0.43) | ACACBACACAPTGDRTHRBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11491133-B2 | Heteroaryl-isochroman compounds and uses thereof | SUNOVION PHARMACEUTICALS INC. (US) | 2022-11-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11491133-B2 | Heteroaryl-isochroman compounds and uses thereof | GRIN2C, INA, SDHA | ACACB 641/4885ACACA 604/4885PTGDR 599/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.