SCHEMBL29985272

SCHEMBL29985272

CC1COC(=O)/C=C\C(=O)OCC(C)OC(=O)/C=C\C(=O)O1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 3/20 0.37
CA1 P00915 3/20 0.36
CA9 Q16790 3/20 0.36
MMP3 P08254 1/20 0.33
ALDH1A1 P00352 1/20 0.33
NPC1 O15118 4/20 0.32
RAB9A P51151 4/20 0.32
LMNA P02545 3/20 0.32
PRNP P04156 2/20 0.32
HTT P42858 2/20 0.32
THRB P10828 1/20 0.32
NR0B1 P51843 1/20 0.32
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32
HIF1A Q16665 1/20 0.32
KDM4E B2RXH2 1/20 0.32
GMNN O75496 1/20 0.30
MTOR P42345 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL250404 1.00 SMN1; SMN2 (0.37) SMN1; SMN2CA1CA9MMP3ALDH1A1
SCHEMBL30269 1.00 SMN1; SMN2 (0.37) SMN1; SMN2CA1CA9MMP3ALDH1A1
SCHEMBL30272 1.00 SMN1; SMN2 (0.37) SMN1; SMN2CA1CA9MMP3ALDH1A1
Ethylene SCHEMBL11669780 0.96 SMN1; SMN2 (0.34) SMN1; SMN2CA1CA9MMP3ALDH1A1
Ethylene SCHEMBL6720301 0.96 SMN1; SMN2 (0.34) SMN1; SMN2CA1CA9MMP3ALDH1A1
Ethylene Glycol SCHEMBL28457562 0.90 MMP3 (0.35) SMN1; SMN2CA1CA9MMP3NPC1
Ethylene Glycol SCHEMBL28461659 0.90 MMP3 (0.35) SMN1; SMN2CA1CA9MMP3NPC1
Ethylene Glycol SCHEMBL29155627 0.90 MMP3 (0.35) SMN1; SMN2CA1CA9MMP3NPC1
Ethylene Glycol SCHEMBL28898450 0.90 MMP3 (0.35) SMN1; SMN2CA1CA9MMP3NPC1
SCHEMBL10981369 0.89 CA1 (0.33) SMN1; SMN2CA1CA9NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113354904-B Polymer elastomer based on crystalline phase transition and shape memory behavior regulation and control method thereof 浙江大学衢州研究院 2022-11-08 CN claimed